Anti-NALP10 NLRP10 Antibody

Product Name

Anti-NALP10 NLRP10 Antibody

View all NLRP10/Pynod/NALP10 Antibodies

SKU/Catalog Number

A08124

Size

0.1 mg

Form

Liquid

Description

Boster Bio Anti-NALP10 NLRP10 Antibody (Catalog # A08124). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human.

Storage & Handling

NALP10 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Cite This Product

Anti-NALP10 NLRP10 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A08124)

Host

Rabbit

Contents

NALP10 Antibody is supplied in PBS containing 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Immunogen

NALP10 antibody was raised against a 14 amino acid synthetic peptide near the amino terminus of human NALP10. The immunogen is located within the first 50 amino acids of NALP10.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

This antibody will not cross-react with JMJD1A or JMJD1C.

Reactive Species

A08124 is reactive to NLRP10 in Human

Reconstitution

Observed Molecular Weight

68 kDa

Calculated molecular weight

75032 MW

Background of NLRP10/Pynod/NALP10

NALP proteins are cytoplasmic proteins that form a subfamily within the larger CATERPILLER family and are thought to play a crucial role in cell proliferation and reproduction. Like all other NALP family members, NALP10 has a C-terminal leucine-rich repeat (LRR) region, an N-terminal Pyrin domain (PYD) followed by a NACHT domain, and a NACHT-associated domain. It was initially identified as PYNOD, an Apaf-1-like protein that binds to ASC, caspase-1 and IL-1β, inhibiting the autoprocessing of caspase-1, caspase-1-mediated IL-1β processing, and ASC aggregation. NALP10 is thus a potent regulator of apoptosis and inflammation.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

View more details

Applications

A08124 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

NALP10 antibody can be used for detection of NALP10 by Western blot at 1 μg/mL. Antibody can also be used for immunohistochemistry starting at 10 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.

Validation Images & Assay Conditions

Gene/Protein Information For NLRP10 (Source: Uniprot.org, NCBI)

Alternative Names

NOD8, PAN5, PYNOD, NALP10, CLR11.1, NOD8, NACHT, LRR and PYD domains-containing protein 10, Nucleotide-binding oligomerization domain protein 8 Nlrp10|6430548I20Rik, Na, Nalp10, Napl10, PAN5, Py, Pynod|NLR family, pyrin domain containing 10|NACHT, LRR and PYD domains-containing protein 10|NACHT, LRR and PYD containing protein 10|NACHT, leucine rich repeat and PYD containing 10|NACHT/LRR/pyrin domain-containing protein 10|neuronal apoptosis inhibitor protein 10

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

Here are featured tools and databases that you might find useful.

• Boster's Pathways Library
• Protein Databases
• Bioscience Research Protocol Resources
• Data Processing & Analysis Software
• Photo Editing Software
• Scientific Literature Resources
• Research Paper Management Tools
• Molecular Biology Software
• Primer Design Tools
• Bioinformatics Tools
• Phylogenetic Tree Analysis