Anti-Myc POLE Antibody

Product Name

Anti-Myc POLE Antibody

View all DNA Polymerase epsilon catalytic subunit A Antibodies

SKU/Catalog Number

A00112

Size

100 µl

Form

Liquid

Description

Boster Bio Anti-Myc POLE Antibody (Catalog # A00112). Tested in IHC applications. This antibody reacts with Human, Mouse.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-Myc POLE Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A00112)

Host

Rabbit

Contents

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from internal of human POLE1.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross reactivity with other proteins.

Reactive Species

A00112 is reactive to POLE in Human, Mouse

Applications

A00112 is guaranteed for IHC Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

261518 MW

Background of DNA Polymerase epsilon catalytic subunit A

Participates in DNA repair and in chromosomal DNA replication.

Kesti T., J. Biol. Chem. 268:10238-10245(1993).
Syvaeoja J.E.;Submitted (JUN-1998) to the EMBL/GenBank/DDBJ databases.
Asahara H., Submitted (FEB-1996) to the EMBL/GenBank/DDBJ databases.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Immunohistochemistry: 1:50~1:100

Validation Images & Assay Conditions

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Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using POLE1 antibody A00112.

Gene/Protein Information For POLE (Source: Uniprot.org, NCBI)

Alternative Names

DKFZp434F222; DNA polymerase epsilon catalytic subunit A; DNA polymerase II subunit A; EC 2.7.7; EC 2.7.7.7; POLE1FLJ21434; polymerase (DNA directed), epsilon POLE CRCS12, FILS, IMAGEI1, POLE DNA polymerase epsilon, catalytic subunit DNA polymerase epsilon catalytic subunit A|3-5 exodeoxyribonuclease|DNA polymerase II subunit A|DNA polymerase epsilon catalytic subunit protein|polymerase (DNA directed), epsilon, catalytic subunit|polymerase (DNA) epsilon, catalytic subunit

For more info on POLE, check out the POLE Infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for POLE: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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