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Product Info Summary
| SKU: | A00112 |
|---|---|
| Size: | 100 µl |
| Reactive Species: | Human, Mouse |
| Host: | Rabbit |
| Application: | IHC |
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Product info
Product Name
Anti-Myc POLE Antibody
View all DNA Polymerase epsilon catalytic subunit A Antibodies
SKU/Catalog Number
A00112
Size
100 µl
Form
Liquid
Description
Boster Bio Anti-Myc POLE Antibody (Catalog # A00112). Tested in IHC applications. This antibody reacts with Human, Mouse.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-Myc POLE Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A00112)
Host
Rabbit
Contents
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from internal of human POLE1.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
No cross reactivity with other proteins.
Reactive Species
A00112 is reactive to POLE in Human, Mouse
Reconstitution
Calculated molecular weight
261518 MW
Background of DNA Polymerase epsilon catalytic subunit A
Participates in DNA repair and in chromosomal DNA replication.
Kesti T., J. Biol. Chem. 268:10238-10245(1993).
Syvaeoja J.E.;Submitted (JUN-1998) to the EMBL/GenBank/DDBJ databases.
Asahara H., Submitted (FEB-1996) to the EMBL/GenBank/DDBJ databases.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A00112 is guaranteed for IHC Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Immunohistochemistry: 1:50~1:100
Validation Images & Assay Conditions
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Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using POLE1 antibody A00112.
Protein Target Info & Infographic
Gene/Protein Information For POLE (Source: Uniprot.org, NCBI)
Gene Name
POLE
Full Name
DNA polymerase epsilon catalytic subunit A
Weight
261518 MW
Superfamily
DNA polymerase type-B family
Alternative Names
DNA polymerase epsilon catalytic subunit A;2.7.7.7;DNA polymerase II subunit A;POLE;POLE1; POLE CRCS12, FILS, IMAGEI1, POLE DNA polymerase epsilon, catalytic subunit DNA polymerase epsilon catalytic subunit A|3-5 exodeoxyribonuclease|DNA polymerase II subunit A|DNA polymerase epsilon catalytic subunit protein|polymerase (DNA directed), epsilon, catalytic subunit|polymerase (DNA) epsilon, catalytic subunit
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on POLE, check out the POLE Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for POLE: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Myc POLE Antibody (A00112)
Hello CJ!
A00112 has been cited in 1 publications:
*The publications in this section are manually curated by our staff scientists. They may differ from Bioz's machine gathered results. Both are accurate. If you find a publication citing this product but is missing from this list, please let us know we will issue you a thank-you coupon.
Wang Ph, Gu Zh, Wan Dh, Zhu Wb, Qiu W, Weng Sp, Yu Xq, He Jg. Plos One. 2013;8(2):E52088. Doi: 10.1371/Journal.Pone.0052088. Epub 2013 Feb 6. Litopenaeus Vannamei Sterile-Alpha And Armadillo Motif Containing Protein (Lvsarm) Is Involved In Regulat...
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