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Product Info Summary
| SKU: | M02997-3 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Mouse |
| Host: | Rat |
| Application: | Flow Cytometry, IP, IHC-F, WB |
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Product info
Product Name
Anti-Ms CD105 Purified Eng Monoclonal Antibody
View all Endoglin/CD105 Antibodies
SKU/Catalog Number
M02997-3
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-Ms CD105 Purified Eng Monoclonal Antibody (Catalog# M02997-3). Tested in Flow Cytometry, IP, WB, IHC-F application(s). This antibody reacts with Mouse.
Storage & Handling
Store at 2-8°C. Do not freeze.
Cite This Product
Anti-Ms CD105 Purified Eng Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M02997-3)
Host
Rat
Contents
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Clonality
Monoclonal
Clone Number
MJ7/18
Isotype
Rat IgG2a kappa
Immunogen
Inflamed mouse skin. The rat monoclonal antibody MJ7/18 reacts with an extracellular epitope of CD105 (Endoglin), a 90 kDa type I homodimerizing membrane glycoprotein expressed on vascular endothelial cells (small and large vessels), activated monocytes and tissue macrophages, stromal cells of certain tissues including bone marrow, pre-B lymphocytes in fetal marrow and erythroid precursors in fetal and adult bone marrow.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
M02997-3 is reactive to Eng in Mouse
Reconstitution
Observed Molecular Weight
19 kDa
Calculated molecular weight
70021 MW
Background of Endoglin/CD105
CD105 (endoglin) is a homodimeric transmembrane glycoprotein serving in presence of TGFbetaR-2 as a receptor for TGFbeta-1 and TGFbeta-3. CD105 is highly expressed on endothelial cells and promotes angiogenesis during wound healing, infarcts and in a wide range of tumours and its gene expression is stimulated by hypoxia. CD105 prevents apoptosis in hypoxic endothelial cells and also antagonises the inhibitory effects of TGFbeta-1 on vascular endothelial cell growth and migration. Normal cellular levels of CD105 are required for formation of new blood vessels.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
M02997-3 is guaranteed for Flow Cytometry, IP, IHC-F, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Flow cytometry: 1-4 μg/ml.
Validation Images & Assay Conditions
There are currently no images for this product. We are working on uploading them please check back shortly or contact us to expedite our upload process for this antibody.
Protein Target Info & Infographic
Gene/Protein Information For Eng (Source: Uniprot.org, NCBI)
Gene Name
Eng
Full Name
Endoglin
Weight
70021 MW
Alternative Names
Endoglin, END, ENG ENG END, HHT1, ORW1 endoglin endoglin|CD105
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on Eng, check out the Eng Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for Eng: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Ms CD105 Purified Eng Monoclonal Antibody (M02997-3)
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