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- Table of Contents
1 Citations 6 Q&As
10 Citations
4 Citations 7 Q&As
10 Citations
Facts about Endoglin.
Required for normal extraembryonic angiogenesis and for embryonic heart development (By similarity). May regulate endothelial cell shape changes in response to blood flow, which drive vascular remodeling and establishment of normal vascular morphology during angiogenesis (By similarity).
Human | |
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Gene Name: | ENG |
Uniprot: | P17813 |
Entrez: | 2022 |
Belongs to: |
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No superfamily |
CD105 antigen; CD105; Endoglin; ENDOsler-Rendu-Weber syndrome 1; ENG; HHT1FLJ41744; ORW; ORW1
Mass (kDA):
70.578 kDA
Human | |
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Location: | 9q34.11 |
Sequence: | 9; NC_000009.12 (127815012..127854773, complement) |
Detected on umbilical veil endothelial cells (PubMed:10625079). Detected in placenta (at protein level) (PubMed:1692830). Detected on endothelial cells (PubMed:1692830).
Cell membrane; Single-pass type I membrane protein.
PMID: 8370410 by Bellon T., et al. Identification and expression of two forms of the human transforming growth factor-beta-binding protein endoglin with distinct cytoplasmic regions.
PMID: 1692830 by Gougos A., et al. Primary structure of endoglin, an RGD-containing glycoprotein of human endothelial cells.
*More publications can be found for each product on its corresponding product page