Anti-MMP8 Antibody Picoband®

MMP-8 antibody

Boster Bio Anti-MMP8 Antibody Picoband® catalog # PB9726. Tested in ELISA, IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance. Cited in 5 publication(s).

Product Info Summary

SKU: PB9726
Size: 100 μg/vial
Reactive Species: Human
Host: Rabbit
Application: ELISA, IHC, WB

Product Name

Anti-MMP8 Antibody Picoband®

View all MMP-8 Antibodies

SKU/Catalog Number

PB9726

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-MMP8 Antibody Picoband® catalog # PB9726. Tested in ELISA, IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-MMP8 Antibody Picoband® (Boster Biological Technology, Pleasanton CA, USA, Catalog # PB9726)

Host

Rabbit

Contents

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

A synthetic peptide corresponding to a sequence at the N-terminus of human MMP-8, different from the related mouse sequence by eleven amino acids.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross-reactivity with other proteins.

Reactive Species

PB9726 is reactive to MMP8 in Human

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Observed Molecular Weight

60 kDa

Calculated molecular weight

53412 MW

Background of MMP-8

MMP8 (Matrix metalloproteinase 8) is a member of the family of matrix metalloproteinases. It is distinct from the collagenase of skin fibroblasts and synovial cells in substrate specificity and immunologic crossreactivity. MMP8 is mapped to 11q21-q22. MMP8 is an enzyme that degrades fibrillar collagens imparting strength to the fetal membranes, is expressed by leukocytes and chorionic cytotrophoblast cells. The enzyme exhibits 58% homology to human fibroblast collagenase and has the same domain structure. It consists of a 20-residue signal peptide, and an 80-residue propeptide that is lost on autolytic activation by cleavage of an M-L bond. MMP8 was found to possess 57% identity with the deduced protein sequence for fibroblast collagenase with 72% chemical similarity. Matrix metalloproteinases (MMPs) have fundamental roles in tumor progression, but most clinical trials with MMP inhibitors have not shown improvements in individuals with cancer. MMP8 has a paradoxical protective role in cancer and provides a genetic model to evaluate the molecular basis of gender differences in cancer susceptibility.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

PB9726 is guaranteed for ELISA, IHC, WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml, Human, By Heat
ELISA, 0.1-0.5μg/ml, -
Western blot, 0.1-0.5μg/ml, Human

Positive Control

WB: K562 Whole Cell, JURKAT Whole Cell
IHC: Human Appendicitis tissue

Validation Images & Assay Conditions

Gene/Protein Information For MMP8 (Source: Uniprot.org, NCBI)

Gene Name

MMP8

Full Name

Neutrophil collagenase

Weight

53412 MW

Superfamily

peptidase M10A family

Alternative Names

Neutrophil collagenase;3.4.24.34;Matrix metalloproteinase-8;MMP-8;PMNL collagenase;PMNL-CL;MMP8;CLG1; MMP8 CLG1, HNC, MMP-8, PMNL-CL matrix metallopeptidase 8 neutrophil collagenase|PMN leukocyte collagenase|PMNL collagenase|collagenase 2|matrix metalloproteinase 8 (neutrophil collagenase)|matrix metalloproteinase-8

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on MMP8, check out the MMP8 Infographic

MMP8 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for MMP8: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

Hello CJ!

PB9726 has been cited in 5 publications:

*The publications in this section are manually curated by our staff scientists. They may differ from Bioz's machine gathered results. Both are accurate. If you find a publication citing this product but is missing from this list, please let us know we will issue you a thank-you coupon.

Sustained Neurotrophin Release from Protein Nanoparticles Mediated by Matrix Metalloproteinases Induces the Alignment and Differentiation of Nerve Cells Yuka Matsuzaki,et al. Biomolecules. 2019 Oct; 9(10): 510. Published online 2019 Sep 20. doi: 10.339

Prevotella intermedia upregulates MMP-1 and MMP-8 expression in human periodontal ligament cells

Glycyrrhizic acid alleviates bleomycin-induced pulmonary fibrosis in rats

Hydrogen sulfide attenuates myocardial fibrosis in diabetic rats through the JAK/STAT signaling pathway

Expression of matrix metalloproteinases-8 and -9 and their tissue inhibitor in the condyles of diabetic rats with mandibular advancement

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Order DetailsPrice
PB9726

100μg

$370
PB9726-10ug

10μg sample (liquid)

$99
PB9726-Biotin

100 μg Biotin conjugated

$570
PB9726-Cy3

100 μg Cy3 conjugated

$570
PB9726-Dylight488

100 μg Dylight488 conjugated

$570
PB9726-Dylight550

100 μg Dylight550 conjugated

$570
PB9726-Dylight594

100 μg Dylight594 conjugated

$570
PB9726-FITC

100 μg FITC conjugated

$570
PB9726-HRP

100 μg HRP conjugated

$570
PB9726-APC

100 μg APC conjugated

$670
PB9726-PE

100 μg PE conjugated

$670
PB9726-iFluor647

100 μg iFluor647 conjugated

$670
PB9726-carrier-free

Carrier Free

$370

More conjugates/formats

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PB9726
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$370.00

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