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Product Info Summary
| SKU: | A08709 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human |
| Host: | Rabbit |
| Application: | ELISA, WB |
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Product info
Product Name
Anti-MLX-interacting protein MLXIP Antibody
SKU/Catalog Number
A08709
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-MLX-interacting protein MLXIP Antibody (Catalog # A08709). Tested in ELISA, WB applications. This antibody reacts with Human.
Storage & Handling
MLXIP antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-MLX-interacting protein MLXIP Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A08709)
Host
Rabbit
Contents
MLXIP Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
MLXIP antibody was raised against a peptide corresponding to 19 amino acids near the amino terminus of human MLXIP.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
Multiple isoforms of FNIP2 are known to exist. This antibody is predicted to not cross-react with FNIP1.
Reactive Species
A08709 is reactive to MLXIP in Human
Reconstitution
Observed Molecular Weight
68 kDa
Calculated molecular weight
101185 MW
Background of MLXIP
MLXIP is a member of the Myc superfamily of transcription factors and functions as part of a heterodimer with Max-like protein X (MLX) to activate transcription (1). MLXIP contributes to the regulation of glucose homeostasis as the MLXIP/MLX heterodimer activates expression of thioredoxin-interacting protein (TXNIP), a potent inhibitor of cellular glucose uptake and aerobic glycolysis. The mammalian target of rapamycin (mTOR) suppresses the activation of the TXNIP pathway by binding to MLXIP, thereby preventing the MLXIP/MLX heterodimer formation (2). MLXIP interaction with Myc may also be involved in metabolic reprogramming and tumorigenesis (3).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A08709 is guaranteed for ELISA, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
MLXIP antibody can be used for Western blot at 1 - 2 μg/mL.
Antibody validated: Western Blot in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of MLXIP in MCF7 cell lysate with MLXIP antibody at 1 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For MLXIP (Source: Uniprot.org, NCBI)
Gene Name
MLXIP
Full Name
MLX-interacting protein
Weight
101185 MW
Alternative Names
FB22, HM89, LAP3, LCR1, NPYR, WHIM, CD184, LESTR, NPY3R, NPYRL, HSY3RR, NPYY3R, D2S201E MLXIP MIR, MONDOA, bHLHe36 MLX interacting protein MLX-interacting protein|Mlx interactor|class E basic helix-loop-helix protein 36|transcriptional activator MondoA
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on MLXIP, check out the MLXIP Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for MLXIP: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-MLX-interacting protein MLXIP Antibody (A08709)
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No publications found for A08709
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