MLX-interacting protein Antibodies

AND MLXIP ELISA kits, MLX-interacting protein Proteins

Many biological assays use antibodies to detect MLX-interacting protein, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with MLX-interacting protein in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop MLX-interacting protein antibodies...

We validate the specificity of these antibodies to MLX-interacting protein by testing them on tissues known to express MLXIP positively and negatively. Browse below to find the MLXIP antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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MLXIP Infographic by Boster Bio

All MLXIP Products

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Product

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Specificity

Applications

Price

Anti-MLX-interacting protein MLXIP Antibody

Human

ELISA, WB

$449
Cat # A08709
0.1 mg

Anti-MLX-interacting protein/MLXIP Antibody Picoband®

Human, Rat

ELISA, Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # A08709-2
100 μg/vial

MLX interacting protein (MLXIP) (NM_014938) Human Over-expression Lysate

Human

$960
Cat # LS022877
100 µg

MLXIP Overview

Facts about MLX-interacting protein.

MLXIP 3D structure. Source: alphafold

MLX-interacting protein (MLXIP)

Binds DNA as a heterodimer with MLX and activates transcription.
Binds to the canonical E box sequence 5'-CACGTG-3'.

Plays a role in transcriptional activation of glycolytic target genes. Involved in glucose-responsive gene regulation.

Gene Information

Human
Gene Name:	MLXIP
Uniprot:	Q9HAP2
Entrez:	22877

Family

Belongs to:

No superfamily

Alternative Names

bHLHe36BHLHE36; Class E basic helix-loop-helix protein 36; KIAA0867MondoA; MIRMLX-interacting protein; MLX interacting protein; MONDOAMlx interactor; Transcriptional activator MondoA

Molecular Weight

Mass (kDA):
101.185 kDA

Genomic Context


Human

Location:	12q24.31
Sequence:	12; NC_000012.12 (122078744..122147344)

Tissue Specificity

Widely expressed in adult tissues. Most abundant in skeletal muscle.

Subcellular Localizations

Cytoplasm. Nucleus. Mitochondrion outer membrane. Predominantly cytoplasmic but shuttles between cytoplasm and nucleus when associated with MLX. Also associates with the outer mitochondrial membrane and may shuttle between the outer mitochondrial membrane and the nucleus.

Diseases

Malignant Neoplasms
Cell Invasion
Malignant Paraganglionic Neoplasm
Acute Lymphocytic Leukemia
Neoplasm Invasiveness
Insulin Resistance
Malignant Childhood Neoplasm
Neoplasms
Malignant Ascites

Leukemia
Inflammation
Malignant Neoplasm Of Ovary
Epithelial Ovarian Cancer

Pathways

Sensitization
Cell Migration
Rna Interference
Glycolysis

PTMs

Acetylation

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MLXIP

References

PMID: 11073985 by Billin A.N., et al. MondoA, a novel basic helix-loop-helix-leucine zipper transcriptional activator that constitutes a positive branch of a max-like network.

PMID: 12446771 by Eilers A.L., et al. A novel heterodimerization domain, CRM1, and 14-3-3 control subcellular localization of the MondoA-Mlx heterocomplex.