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Product Info Summary
| SKU: | A08533 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human |
| Host: | Rabbit |
| Application: | ELISA, IF, IHC-P, WB |
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Product info
Product Name
Anti-MAP1LC3C Antibody
SKU/Catalog Number
A08533
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-MAP1LC3C Antibody (Catalog # A08533). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human.
Storage & Handling
MAP1LC3C antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Cite This Product
Anti-MAP1LC3C Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A08533)
Host
Rabbit
Contents
MAP1LC3C antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
MAP1LC3C antibody was raised against an 18 amino acid peptide near the carboxy terminus of human MAP1LC3C. The immunogen is located within the last 50 amino acids of MAP1LC3C.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
MAP1LC3C antibody is human, mouse and rat reactive. Multiple isoforms MAP1LC3C are known to exist. MAP1LC3C antibody is predicted to not cross-react with MAP1LC3A or MAP1LC3B.
Reactive Species
A08533 is reactive to MAP1LC3C in Human
Reconstitution
Observed Molecular Weight
68 kDa
Calculated molecular weight
16852 MW
Background of LC3C
Microtubule-associated proteins (MAPs) regulate microtubule stability and play critical roles in neuronal development and plasticity (1). MAP1LC3C belongs to the MAP1 LC3 family of proteins that form mature complexes with MAP1A and MAP1B which are thought to be important in the formation and development of axons and dendrites (2). MAP1LC3C is one of three isoforms of MAP1LC3, the mammalian homolog of yeast ATG8, an essential autophagy protein. These isoforms exhibit distinct expression patterns and MAP1LC3C, like MAP1LC3A but not MAP1LC3B, is post-translationally modified, suggesting the three isoforms may have different physiological functions (3).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A08533 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
MAP1LC3C antibody can be used for detection of MAP1LC3C by Western blot at 1 - 2 μg/ml. Antibody can also be used for Immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of MAP1LC3C in human brain tissue lysate with MAP1LC3C antibody at 1 μg/ml in (A) the absence and (B) the presence of blocking peptide.
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Immunohistochemistry of MAP1LC3C in human brain tissue with MAP1LC3C antibody at 5 μg/mL.
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Immunofluorescence of MAP1LC3C in human brain tissue with MAP1LC3C antibody at 20 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For MAP1LC3C (Source: Uniprot.org, NCBI)
Gene Name
MAP1LC3C
Full Name
Microtubule-associated proteins 1A/1B light chain 3C
Weight
16852 MW
Superfamily
ATG8 family
Alternative Names
LC3C, ATG8JAutophagy-related protein LC3 C MAP1LC3C ATG8J, LC3C microtubule associated protein 1 light chain 3 gamma microtubule-associated proteins 1A/1B light chain 3C|LC3-like protein 2|MAP1 light chain 3-like protein 2|MAP1 light chain 3-like protein 3|MAP1A/MAP1B LC3 C|MAP1A/MAP1B light chain 3 C|autophagy-related protein LC3 C|autophagy-related ubiquitin-like modifier LC3 C
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on MAP1LC3C, check out the MAP1LC3C Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for MAP1LC3C: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-MAP1LC3C Antibody (A08533)
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