MAP1LC3C Antibodies

AND MAP1LC3C ELISA kits, MAP1LC3C Proteins

Many biological assays use antibodies to detect MAP1LC3C, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with MAP1LC3C in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop MAP1LC3C antibodies...

We validate the specificity of these antibodies to MAP1LC3C by testing them on tissues known to express MAP1LC3C positively and negatively. Browse below to find the MAP1LC3C antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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MAP1LC3C Infographic by Boster Bio

All MAP1LC3C Products

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Product

Figures

Specificity

Applications

Price

Anti-MAP1LC3C Antibody

Human

ELISA, IF, IHC-P, WB

$449
Cat # A08533
0.1 mg

Anti-MAP1LC3C (P77) Antibody

Human, Mouse, Rat

$405
Cat # A08533-1
100ul

MAP1LC3C Overview

Facts about Microtubule-associated proteins 1A/1B light chain 3C.

MAP1LC3C 3D structure. Source: alphafold

Microtubule-associated proteins 1A/1B light chain 3C (MAP1LC3C)

Ubiquitin-like modifier that plays an essential role in antibacterial autophagy (xenophagy) through the selective binding of CALCOCO2. Recruits all ATG8 family members to infecting bacteria like S.

Typhimurium (PubMed:23022382). May also play a role in aggrephagy, the macroautophagic degradation of ubiquitinated and aggregated proteins (PubMed:28404643).

Gene Information

Human
Gene Name:	MAP1LC3C
Uniprot:	Q9BXW4
Entrez:	440738

Family

Belongs to:

ATG8 family

Alternative Names

ATG8J; Autophagy-related protein LC3 C; Autophagy-related ubiquitin-like modifier LC3 C; LC3C; LC3-like protein 2; MAP1 light chain 3-like protein 2; MAP1 light chain 3-like protein 3; MAP1A/MAP1B LC3 C; microtubule-associated protein 1 light chain 3 gammaMAP1A/MAP1B light chain 3 C; microtubule-associated proteins 1A/1B light chain 3C

Molecular Weight

Mass (kDA):
16.852 kDA

Genomic Context


Human

Location:	1q43
Sequence:	1; NC_000001.11 (241995194..242001393, complement)

Tissue Specificity

Most abundant in placenta, lung and ovary.

Subcellular Localizations

Cytoplasm, cytoskeleton. Endomembrane system; Lipid-anchor. Cytoplasmic vesicle, autophagosome membrane; Lipid-anchor. Cytoplasmic vesicle, autophagosome. LC3-II binds to the autophagic membranes.

Diseases

Neoplasms
Malignant Neoplasm Of Prostate
Malignant Neoplasms
Glioma
Pathological Dilatation
Malignant Paraganglionic Neoplasm
Malignant Glioma

Brain Neoplasms

Interacting Proteins

ATG101
ATG13
ATG16L1
ATG4B
DNAAF4

FYCO1
IPO5
KBTBD6
KBTBD7
NBR1

NEK9
NIPSNAP2
RASSF1
RASSF5
SF3A1

SQSTM1
STK3
TBC1D2B
TECPR2
TP53INP1

UBA5
ULK1
WDFY3

Pathways

Autophagy
Cell Death
Cell Growth
Rna Interference
Conjugation
Localization

PTMs

Cleavage

Phosphorylation

Ubiquitination

Research Areas

Autophagy
Cellular Markers

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MAP1LC3C

References

PMID: 12740394 by He H., et al. Post-translational modifications of three members of the human MAP1LC3 family and detection of a novel type of modification for MAP1LC3B.

PMID: 15187094 by Tanida I., et al. HsAtg4B/HsApg4B/autophagin-1 cleaves the carboxyl termini of three human Atg8 homologues and delipidates microtubule-associated protein light chain 3- and GABAA receptor-associated protein-phospholipid conjugates.