Anti-Monoamine Oxidase B/MAOB Antibody Picoband®

Product Name

Anti-Monoamine Oxidase B/MAOB Antibody Picoband®

View all Monoamine Oxidase B Antibodies

SKU/Catalog Number

PA1649

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-Monoamine Oxidase B/MAOB Antibody catalog # PA1649. Tested in IHC, WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-Monoamine Oxidase B/MAOB Antibody Picoband® (Boster Biological Technology, Pleasanton CA, USA, Catalog # PA1649)

Host

Rabbit

Contents

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

A synthetic peptide corresponding to a sequence at the N-terminus of mouse MAOB, identical to the related rat sequence.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross-reactivity with other proteins

Reactive Species

PA1649 is reactive to Maob in Mouse, Rat

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Observed Molecular Weight

59 kDa

Calculated molecular weight

58558 MW

Background of Monoamine Oxidase B

MAOB (MONOAMINE OXIDASE B), also called MAO, BRAIN, AMINE OXIDASE (FLAVIN-CONTAINING) B, is a protein that in humans is encoded by the MAOB gene. MAOB is a member of the flavin monoamine oxidase family. And it is mapped on Xp11.3. MAOB catalyzes the oxidative deamination of biogenic and xenobiotic amines and plays an important role in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. This protein preferentially degrades benzylamine and phenylethylamine. Like MAOA, it also degrades dopamine. MAO-B is involved in the breakdown of dopamine, a neurotransmitter implicated in reinforcing and motivating behaviors as well as movement. MAO-B inhibition is, therefore, associated with enhanced activity of dopamine, as well as with decreased production of hydrogen peroxide, a source of reactive oxygen species.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

View more details

Applications

PA1649 is guaranteed for IHC, WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml, Mouse, Rat, By Heat
Western blot, 0.1-0.5μg/ml, Mouse, Rat

Positive Control

WB: Mouse Liver Tissue, Mouse Lung Tissue, Rat Kidney Tissue, Rat Brain Tissue, Rat Liver Tissue, Rat Lung Tissue
IHC: Rat Liver Tissue

Validation Images & Assay Conditions

Gene/Protein Information For Maob (Source: Uniprot.org, NCBI)

Alternative Names

Amine oxidase [flavin-containing] B;1.4.3.4;Monoamine oxidase type B;MAO-B;Maob; MAOB monoamine oxidase B amine oxidase [flavin-containing] B|MAO, brain|MAO, platelet|MAO-B|adrenalin oxidase|monoamine oxidase type B|tyramine oxidase

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

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