MAOB Antibodies

Amine oxidase [flavin-containing] B (MAOB)

Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOB preferentially degrades benzylamine and phenylethylamine.

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Gene Information

Human
Gene Name:	MAOB
Uniprot:	P27338
Entrez:	4129

Family

Belongs to:
flavin monoamine oxidase family

Alternative Names

adrenalin oxidase; amine oxidase [flavin-containing] B; EC 1.4.3; EC 1.4.3.4; MAO, brain; MAO, platelet; MAO-B; MGC26382; monoamine oxidase B; Monoamine oxidase type B; tyramine oxidase

Molecular Weight

Mass (kDA):
58.763 kDA

Genomic Context

Human
Location:	Xp11.3
Sequence:	X; NC_000023.11 (43766610..43882450, complement)

Subcellular Localizations

Mitochondrion outer membrane; Single-pass type IV membrane protein; Cytoplasmic side.

Diseases

• Parkinson Disease
• Mental Disorders
• Norrie Disease
• Blind Vision
• Schizophrenia
• Depressive Disorder
• Mood Disorders
• Attention Deficit Hyperactivity Disorder
• Dysequilibrium Syndrome
• Variable Number Tandem Repeat
• Nervousness

• Epilepsy
• Alzheimer's Disease
• Malnutrition
• Secondary Parkinson Disease
• Neurodegenerative Disorders

Interacting Proteins

• MAOA

Pathways

• Localization
• Pathogenesis
• Methylation
• Locomotion
• Transport
• Brain Development
• Amygdala Development
• Immune Response
• Serotonin Uptake
• Platelet Aggregation
• Mrna Transcription
• Vocalization Behavior

• Embryo Implantation
• Cognition
• Exocytosis
• Cell Proliferation
• Exploration Behavior
• Insulin Secretion
• Dna Methylation

PTMs

• Deamination
• Methylation

• Oxidation
• Phosphorylation

• Acetylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MAOB

Boster Bio MAOB Marker

Are you searching for a brand new MAOB antibody to aid in your research? If you are, then you're in the right place. This Boster Bio MAOB Marker has been tested for WB, ICC, and Immunofluorescence. It has been validated by using negative and positive samples to ensure high affinity and specificity. Boster also provides product credit to early reviewers. This is done to reward scientists all over the globe.

Boster Bio Anti-Monoamine Oxidase B/MAOB Marker

The Boster Bio Anti-Monoamine Oxide B/MAOB Marker is a monoclonal antibody against the enzyme. It has been tested with different methods and exhibits high sensitivity and specificity. It is available in multiple conjugated forms as well as non-conjugated. It reacts with Mouse, Rat, and Human monoamine oxide (MAO).

Monoamine Oxase B as well as A are mitochondrial-bound enzymes that preferentially process serotonin, norepinephrine, as well as the phenylethylamine. While these two metabolites may be related, they are very different. Monoamine oxidases are found in all types of cells including brain tissue, neurons and even the liver.

Boster validates antibodies against WB, IHC

In addition to producing quality antibodies, Boster Bio also manufactures ELISA kits and reagents. Boster Bio's rigorous validation process and quality standards ensure it to provide antibodies that perform according to the specifications. Their products have been cited in over 29,000 publications and are specifically designed for use on WB, IHC, and ELISA. Boster Bio has a wide assortment of antibodies that cover numerous areas, including neuroscience, immunology and cell biology. Boster Bio's Quality Assurance assures that every product will perform exactly as it is described.

Antibodies from Boster Bio are high-affinity and tested in WB and IHC. Their products have been referenced in peer-reviewed journals for over 25 years and are widely trusted by the research community. They are also validated on Western Blotting, Immunohistochemistry, and ELISA. Boster's antibodies are reliable and save time and money on the research process.

WB is the initial test for validation. However, the results of WB do not necessarily mean that the antibody is extremely specific. Monoclonal antibodies are most effective against native proteins, while denatured proteins don't respond well to them. The IHC and Flow cytometry methods are also beneficial in confirming antibody specificity. IHC and Flowcytometry studies should include a negative control as much as is feasible. A negative control will show whether the secondary antibody is binding to the target cell unspecifically. False positives can also be identified using this negative control.

There are many possibilities of errors in any experiment. To avoid this, it is recommended to conduct a preliminary WB screen. Doing an immunohistochemistry analysis on the antibodies found is essential. Without an accurate western plot the specificity of the antibody can't be confirmed. In certain cases, however, immunoblotting may produce positive results. IHC data will also show good correlation. Boster Bio validates antibodies using IHC, WB, and ICC.

Boster confirms antibodies on ICC

Boster Bio has high affinity primary antibodies that have been used in numerous studies over the last 25 years. Researchers around the globe trust their antibodies. They are validated on Immunohistochemistry, Western Blotting, and ELISA. In addition to ICC, Boster Bio validates their antibodies for use in WB applications. Click on the links below to learn more. They are also available as liquid.

Boster validates antibodies for immunofluorescence

The Boster Bio company makes high affinity primary antibodies, that are tested using a variety of immunofluorescence platforms. Boster's antibodies have been highly referenced over the last 25 years, and are highly regarded by researchers. Immunohistochemistry, Western Blotting, and ELISA have been used to validate the antibodies. Boster's antibody can be used in applications involving immunofluorescence. They are available in solid and liquid forms.

Boster Bio's Anti-AKT AKT1 Antibody (catalog number A00024-1) is one of these antibodies. It has been tested in ELISA and Flow Cytometry as well as Immunofluorescence. This antibody is made from Recombinant Human AKT1 and Human AKT2 proteins. It can be stored at temperatures of 4 degrees Celsius for several months and is compatible with cell culture and Western blotting.

WB is an excellent initial validation. However, the WB results do not prove that a monoclonal antibodies will detect a target proteins. Further validation of the specificity of an antibody can be carried out using immunofluorescence (IHC) and Flow cytometry. These methods are extremely beneficial for IHC experiments because they allow the use of negative controls to identify false positives or binding that is not specific.