Anti-MALT1 Antibody Picoband®

Product Name

Anti-MALT1 Antibody Picoband®

View all MALT1 Antibodies

SKU/Catalog Number

PA1920

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-MALT1 Antibody catalog # PA1920. Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-MALT1 Antibody Picoband® (Boster Biological Technology, Pleasanton CA, USA, Catalog # PA1920)

Host

Rabbit

Contents

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

A synthetic peptide corresponding to a sequence at the C-terminus of human MALT1.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross-reactivity with other proteins

Reactive Species

PA1920 is reactive to MALT1 in Human

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Observed Molecular Weight

22-24 kDa

Calculated molecular weight

92272 MW

Background of MALT1

MALT1 (Mucosa-associated lymphoid tissue lymphoma translocation protein 1), also called MLT or PARACASPASE, is a protein that in humans is encoded by the MALT1 gene. This gene has been found to be recurrently rearranged in chromosomal translocation with two other genes - baculoviral IAP repeat-containing protein 3 (also known as apoptosis inhibitor 2) and immunoglobulin heavy chain locus - in mucosa-associated lymphoid tissue lymphomas. Dierlamm et al. (1999) and Akagi et al. (1999) mapped the MALT1 gene to chromosome 18q21. Using mouse models, Ruland et al. (2003) demonstrated that MALT1 is essential for T-cell activation, proliferation, and IL2 production in response to T-cell receptor ligation and strictly required for signal-specific NF-kappa-B (NFKB) activation induced by the T-cell receptor but not TNF-alpha or IL1 signaling. MALT1 operates downstream of BCL10, controls the catalytic activity of the canonical I-kappa-B kinase complex, and regulates the signaling of JNK and p38 MAP kinases.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

PA1920 is guaranteed for WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blot, 0.1-0.5μg/ml, Human

Positive Control

WB: MCF-7 Cell, HELA Cell

Validation Images & Assay Conditions

Gene/Protein Information For MALT1 (Source: Uniprot.org, NCBI)

Alternative Names

Mucosa-associated lymphoid tissue lymphoma translocation protein 1;3.4.22.-;MALT lymphoma-associated translocation;Paracaspase;MALT1;MLT; MALT1 IMD12, MLT, MLT1, PCASP1 MALT1 paracaspase mucosa-associated lymphoid tissue lymphoma translocation protein 1|MALT1 protease|caspase-like protein|mucosa associated lymphoid tissue lymphoma translocation gene 1|paracaspase-1

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

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