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Product Info Summary
| SKU: | A01240 |
|---|---|
| Size: | 100μl |
| Reactive Species: | Hamster, Human, Monkey, Mouse |
| Host: | Mouse |
| Application: | IF, IHC, WB |
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Product info
Product Name
Anti-LPP Monoclonal Antibody
SKU/Catalog Number
A01240
Size
100μl
Form
Liquid
Description
Boster Bio Anti-LPP Monoclonal Antibody catalog # A01240. Tested in IF, IHC, WB applications. This antibody reacts with Hamster, Human, Monkey, Mouse.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-LPP Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A01240)
Host
Mouse
Contents
Ascitic fluid containing 0.03% sodium azide.
Clonality
Monoclonal
Clone Number
8B3A11
Isotype
IgG
Immunogen
Purified recombinant fragment of human LPP expressed in E. Coli.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
No cross reactivity with other proteins.
Reactive Species
A01240 is reactive to LPP in Hamster, Human, Monkey, Mouse
Applications
A01240 is guaranteed for IF, IHC, WB Boster Guarantee
Observed Molecular Weight
39 kDa
Calculated molecular weight
65746 MW
Background of LPP
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by HDAC5 belongs to the class II histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. It coimmunoprecipitates only with HDAC3 family member and might form multicomplex proteins. It also interacts with myocyte enhancer factor-2 (MEF2) proteins, resulting in repression of MEF2-dependent genes. This gene is thought to be associated with colon cancer. Two transcript variants encoding different isoforms have been found for this gene.
Doppler H, et al. (2005) J Biol Chem. 280(15):15013-15019.
McKinsey TA, et al. (2000) Nature. 408(6808): 106-111.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB, 1:500-1:2000
IHC, 1:200-1:1000
IF, 1:200-1:1000
Validation Images & Assay Conditions
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Immunohistochemistry (IHC) analysis of paraffin-embedded human small intestine with DAB staining using LPP Monoclonal antibody.
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Western Blot (WB) analysis using LPP Monoclonal antibody against HeLa (1), NIH/3T3 (2), COS (3), Caki (4), MCF-7 (5), HepG2 (6) and SMMC-7721 (7) cell lysate.
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Confocal Immunofluorescence (IF) analysis of COS cells using LPP Monoclonal antibody (green). Red: Actin filaments have been labeled using DY-554 phalloidin. Blue: DRAQ5 fluorescent DNA dye.
Protein Target Info & Infographic
Gene/Protein Information For LPP (Source: Uniprot.org, NCBI)
Gene Name
LPP
Full Name
Lipoma-preferred partner
Weight
65746 MW
Superfamily
zyxin/ajuba family
Alternative Names
DKFZp779O0231; FLJ30652; FLJ41512; LIM domain containing preferred translocation partner in lipoma; LIM domain-containing preferred translocation partner in lipoma; LIM protein; lipoma-preferred partner; LPP LPP LIM domain containing preferred translocation partner in lipoma lipoma-preferred partner|LIM protein|lipoma preferred partner
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on LPP, check out the LPP Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for LPP: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-LPP Monoclonal Antibody (A01240)
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No publications found for A01240
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