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Lipoma-preferred partner Antibodies
AND LPP ELISA kits, Lipoma-preferred partner Proteins
Many biological assays use antibodies to detect Lipoma-preferred partner, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Lipoma-preferred partner in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Lipoma-preferred partner antibodies...
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LPP Infographic by Boster Bio
All LPP Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A01240-2
100 μg/vial
Cat # A01240-2
100 μg/vial
LPP Overview
Facts about Lipoma-preferred partner.
Lipoma-preferred partner (LPP)
May play a structural role at sites of cell adhesion in maintaining cell shape and motility. In addition to these structural functions, it might also be implicated in signaling events and activation of gene transcription.
May be involved in signal transduction from cell adhesion sites to the nucleus allowing successful integration of signals arising from soluble factors and cell-cell adhesion sites. Also suggested to serve as a scaffold protein on which distinct protein complexes are assembled in the cytoplasm and in the nucleus.
Gene Information
| Human | |
|---|---|
| Gene Name: | LPP |
| Uniprot: | Q93052 |
| Entrez: | 4026 |
Family
| Belongs to: |
|---|
| zyxin/ajuba family |
Alternative Names
DKFZp779O0231; FLJ30652; FLJ41512; LIM domain containing preferred translocation partner in lipoma; LIM domain-containing preferred translocation partner in lipoma; LIM protein; lipoma-preferred partner; LPP
Molecular Weight
Mass (kDA):
65.746 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 3q27.3-q28 |
| Sequence: | 3; NC_000003.12 (188152152..188890671) |
Tissue Specificity
Expressed in a wide variety of tissues but no or very low expression in brain and peripheral leukocytes.
Subcellular Localizations
Nucleus. Cytoplasm. Cell junction. Cell membrane. Found in the nucleus, in the cytoplasm and at cell adhesion sites. Shuttles between the cytoplasm and the nucleus. It has been found in sites of cell adhesion such as cell-to-cell contact and focal adhesion which are membrane attachment sites of cells to the extracellular matrix. Mainly nuclear when fused with HMGA2/HMGIC and KMT2A/MLL1.
Diseases
- Urinary Incontinence
- Urinary Stress Incontinence
- Urethral Diseases
- Lipoma
- Neoplasms
- Tissue Adhesions
- Depressive Disorder
- Anxiety Disorders
- Pathological Dilatation
- Lichen Disease
- Neurogenic Urinary Bladder
- Salmonella Infections
Interacting Proteins
- LASP1
Pathways
- Localization
- Secretion
- Pathogenesis
- Cell Migration
- Transport
- Synaptic Transmission
- Cell Adhesion
- Reflex
- Immune Response
- Virulence
- Cell Growth
- Lipid Modification
- Translation
PTMs
- Cleavage
- Dephosphorylation
- Phosphorylation
- Oxidation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/LPP
bosterbio.com/bosterbio-gene-info-cards/LPP
References
PMID: 8812423 by Petit M.M.R., et al. LPP, the preferred fusion partner gene of HMGIC in lipomas, is a novel member of the LIM protein gene family.
PMID: 12063392 by Lemke I., et al. A novel LPP fusion gene indicates the crucial role of truncated LPP proteins in lipomas and pulmonary chondroid hamartomas.