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Product Info Summary
| SKU: | A06636-1 |
|---|---|
| Size: | 80 µl |
| Reactive Species: | Human |
| Host: | Rabbit |
| Application: | IHC-P, WB |
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Product info
Product Name
Anti-ITGA8 Antibody (C-term)
View all Integrin alpha 8 Antibodies
SKU/Catalog Number
A06636-1
Size
80 µl
Description
Boster Bio Anti-ITGA8 Antibody (C-term) (Catalog # A06636-1). Tested in IHC-P, WB application(s). This antibody reacts with Human.
Storage & Handling
Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Cite This Product
Anti-ITGA8 Antibody (C-term) (Boster Biological Technology, Pleasanton CA, USA, Catalog # A06636-1)
Host
Rabbit
Contents
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
Clonality
Polyclonal
Isotype
Rabbit IgG
Immunogen
This ITGA8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1025-1053 amino acids from the C-terminal region of human ITGA8.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A06636-1 is reactive to ITGA8 in Human
Reconstitution
Calculated molecular weight
117474 Da
Background of Integrin alpha 8
Integrin alpha-8/beta-1 functions in the genesis of kidney and probably of other organs by regulating the recruitment of mesenchymal cells into epithelial structures. It recognizes the sequence R-G-D in a wide array of ligands including TNC, FN1, SPP1 TGFB1, TGFB3 and VTN. NPNT is probably its functional ligand in kidney genesis. Neuronal receptor for TNC it mediates cell-cell interactions and regulates neurite outgrowth of sensory and motor neurons.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A06636-1 is guaranteed for IHC-P, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:2000
IHC-P: 1:50-1:100
Validation Images & Assay Conditions
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All lanes : Anti-ITGA8 Antibody (C-term) at 1:2000 dilution
Lane 1: Raji whole cell lysate
Lane 2: 293 whole cell lysate
Lane 3: LNCaP whole cell lysate
Lysates/proteins at 20 µg per lane.
Secondary
Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution.
Predicted band size : 117 kDa
Blocking/Dilution buffer: 5% NFDM/TBST.
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Anti-ITGA8 Antibody (C-term) at 1:2000 dilution + K562 whole cell lysate
Lysates/proteins at 20 µg per lane.
Secondary
Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution.
Predicted band size : 117 kDa
Blocking/Dilution buffer: 5% NFDM/TBST.
Click image to see more details
ITGA8 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of ITGA8 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Protein Target Info & Infographic
Gene/Protein Information For ITGA8 (Source: Uniprot.org, NCBI)
Gene Name
ITGA8
Full Name
Integrin alpha-8
Weight
117474 Da
Superfamily
integrin alpha chain family
Alternative Names
Integrin alpha-8, Integrin alpha-8 heavy chain, Integrin alpha-8 light chain, ITGA8 ITGA8 integrin subunit alpha 8 integrin alpha-8|integrin, alpha 8
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on ITGA8, check out the ITGA8 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for ITGA8: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-ITGA8 Antibody (C-term) (A06636-1)
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