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IRF5 Antibodies
AND IRF5 ELISA kits, IRF5 Proteins
Many biological assays use antibodies to detect IRF5, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with IRF5 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop IRF5 antibodies...
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IRF5 Infographic by Boster Bio
All IRF5 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
WB
$370
Cat # PA2208
100 μg/vial
Cat # PA2208
100 μg/vial
Human, Mouse, Rat
Flow Cytometry, IP, IF, IHC, ICC, WB
$370
Cat # M00958
100 μl
Cat # M00958
100 μl
Human, Mouse, Rat
Flow Cytometry, IP, IF, IHC, ICC, WB
$405
Cat # A00958
100ul
Cat # A00958
100ul
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, ICC, WB
$370
Cat # A00958-1
100 µg/vial
Cat # A00958-1
100 µg/vial
IRF5 Overview
Facts about Interferon regulatory factor 5.
Interferon regulatory factor 5 (IRF5)
Transcription factor involved in the induction of interferons IFNA and INFB and inflammatory cytokines upon virus infection. Activated by TLR7 or TLR8 signaling.
.
Gene Information
| Human | |
|---|---|
| Gene Name: | IRF5 |
| Uniprot: | Q13568 |
| Entrez: | 3663 |
Family
| Belongs to: |
|---|
| IRF family |
Alternative Names
IBD14; interferon regulatory factor 5; IRF5; IRF-5; SLEB10
Molecular Weight
Mass (kDA):
56.044 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 7q32.1 |
| Sequence: | 7; NC_000007.14 (128937032..128950042) |
Subcellular Localizations
Cytoplasm. Nucleus. Shuttles between the nucleus and the cytoplasm.
Diseases
- Lupus Erythematosus, Systemic
- Autoimmune Reaction
- Autoimmune Diseases
- Rheumatoid Arthritis
- Arthritis
- Autoimmunity
- Inflammation
- Sclerosis
- Virus Diseases
- Diffuse Scleroderma
- Neoplasms
- Innate Immune Response
- Sjogren's Syndrome
Interacting Proteins
- CREBBP
- MAVS
- RELA
- SGTA
Pathways
- Pathogenesis
- Immune Response
- Localization
- Cell Cycle
- Cytokine Production
- Innate Immune Response
- Secretion
- Cell Cycle Arrest
- Inflammatory Response
- Cell Growth
- Methylation
- Cell Death
- Cell Activation
PTMs
- Phosphorylation
- Methylation
- Ubiquitination
Research Areas
- Apoptosis
- Death Receptor Signaling Pathway
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/IRF5
bosterbio.com/bosterbio-gene-info-cards/IRF5
References
PMID: 11303025 by Barnes B.J., et al. Virus-specific activation of a novel interferon regulatory factor, IRF-5, results in the induction of distinct interferon alpha genes.
PMID: 15695821 by Schoenemeyer A., et al. The interferon regulatory factor, IRF5, is a central mediator of toll-like receptor 7 signaling.