Anti-IRAK/IRAK1 Antibody Picoband®

Product Name

Anti-IRAK/IRAK1 Antibody Picoband®

View all IRAK1 Antibodies

SKU/Catalog Number

PA2183

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-IRAK/IRAK1 Antibody catalog # PA2183. Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-IRAK/IRAK1 Antibody Picoband® (Boster Biological Technology, Pleasanton CA, USA, Catalog # PA2183)

Host

Rabbit

Contents

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

A synthetic peptide corresponding to a sequence at the N-terminus of human IRAK, identical to the related rat and mouse sequences.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross-reactivity with other proteins

Reactive Species

PA2183 is reactive to IRAK1 in Human, Mouse, Rat

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Observed Molecular Weight

274 kDa

Calculated molecular weight

76537 MW

Background of IRAK1

Interleukin-1 receptor-associated kinase 1, also called IRAK1, is an enzyme that in humans is encoded by the IRAK1 gene. By radiation hybrid analysis, this gene is mapped to chromosome Xq28. Serine/threonine-protein kinase plays a critical role in initiating innate immune response against foreign pathogens. This gene involved in Toll-like receptor (TLR) and IL-1R signaling pathways. This gene encodes the interleukin-1 receptor-associated kinase 1, one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. This gene is partially responsible for IL1-induced upregulation of the transcription factor NF-kappa B.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

PA2183 is guaranteed for WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blot, 0.1-0.5μg/ml, Human, Rat, Mouse

Positive Control

WB: Rat Liver Tissue, Human Placenta Tissue, MCF-7 Cell, PANC Cell,

Validation Images & Assay Conditions

Gene/Protein Information For IRAK1 (Source: Uniprot.org, NCBI)

Alternative Names

Interleukin-1 receptor-associated kinase 1;IRAK-1;2.7.11.1;IRAK1;IRAK; IRAK1 IRAK, pelle interleukin 1 receptor associated kinase 1 interleukin-1 receptor-associated kinase 1|IRAK-1|Pelle homolog

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

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