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Product Info Summary
| SKU: | PA2236 |
|---|---|
| Size: | 100 μg/vial |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | IHC, ICC, WB |
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Product info
Product Name
Anti-IRAK2 Antibody Picoband®
SKU/Catalog Number
PA2236
Size
100 μg/vial
Form
Lyophilized
Description
Boster Bio Anti-IRAK2 Antibody catalog # PA2236. Tested in IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Storage & Handling
Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-IRAK2 Antibody Picoband® (Boster Biological Technology, Pleasanton CA, USA, Catalog # PA2236)
Host
Rabbit
Contents
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Clonality
Polyclonal
Isotype
Rabbit IgG
Immunogen
A synthetic peptide corresponding to a sequence at the C-terminus of human IRAK2, different from the related rat sequence by one amino acid, and from the related mouse sequence by three amino acids.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
No cross-reactivity with other proteins
Reactive Species
PA2236 is reactive to IRAK2 in Human, Mouse, Rat
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Observed Molecular Weight
60 kDa
Calculated molecular weight
69433 MW
Background of IRAK2
Interleukin-1 receptor-associated kinase-like 2 is an enzyme that in humans is encoded by the IRAK2 gene. This gene is mapped to 3p25.3. IRAK2 encodes the interleukin-1 receptor-associated kinase 2, one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. IRAK2 is reported to participate in the IL1-induced upregulation of NF-kappaB. It binds to the IL-1 type I receptor following IL-1 engagement, triggering intracellular signaling cascades leading to transcriptional up-regulation and mRNA stabilization.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
PA2236 is guaranteed for IHC, ICC, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Immunocytochemistry , 0.5-1μg/ml, Human, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml, Human, Mouse, Rat, By Heat
Western blot, 0.1-0.5μg/ml, Human, Mouse, Rat
Positive Control
WB: 22RV Cell, A549 Cell, PANC Cell, SMMC Cell
IHC: Human Lung Cancer Tissue, Rat Spleen Tissue
Validation Images & Assay Conditions
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Anti-IRAK2 antibody, PA2236, Western blotting
Lane 1: 22RV Cell Lysate
Lane 2: A549 Cell Lysate
Lane 3: PANC Cell Lysate
Lane 4: SMMC Cell Lysate
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Anti-IRAK2 antibody, PA2236, IHC(P)
IHC(P): Human Lung Cancer Tissue
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Anti-IRAK2 antibody, PA2236, IHC(P)
IHC(P): Rat Spleen Tissue
Protein Target Info & Infographic
Gene/Protein Information For IRAK2 (Source: Uniprot.org, NCBI)
Gene Name
IRAK2
Full Name
Interleukin-1 receptor-associated kinase-like 2
Weight
69433 MW
Superfamily
protein kinase superfamily
Alternative Names
Interleukin-1 receptor-associated kinase-like 2;IRAK-2;IRAK2; IRAK2 IRAK-2 interleukin 1 receptor associated kinase 2 interleukin-1 receptor-associated kinase-like 2
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on IRAK2, check out the IRAK2 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for IRAK2: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-IRAK2 Antibody Picoband® (PA2236)
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No publications found for PA2236
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Customer Q&As
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1 Customer Q&As for Anti-IRAK2 Antibody Picoband®
Question
We are currently using anti-IRAK2 antibody PA2236 for rat tissue, and we are satisfied with the ICC results. The species of reactivity given in the datasheet says human, mouse, rat. Is it possible that the antibody can work on monkey tissues as well?
A. Collins
Verified customer
Asked: 2015-03-16
Answer
The anti-IRAK2 antibody (PA2236) has not been tested for cross reactivity specifically with monkey tissues, but there is a good chance of cross reactivity. We have an innovator award program that if you test this antibody and show it works in monkey you can get your next antibody for free. Please contact me if I can help you with anything.
Boster Scientific Support
Answered: 2015-03-16
