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Product Info Summary
| SKU: | PA1466 |
|---|---|
| Size: | 100 μg/vial |
| Reactive Species: | Mouse |
| Host: | Rabbit |
| Application: | WB |
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Product info
Product Name
Anti-Interleukin-2 IL2 Antibody Picoband®
SKU/Catalog Number
PA1466
Size
100 μg/vial
Form
Lyophilized
Description
Boster Bio Anti-Interleukin-2 IL2 Antibody catalog # PA1466. Tested in WB applications. This antibody reacts with Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Storage & Handling
Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-Interleukin-2 IL2 Antibody Picoband® (Boster Biological Technology, Pleasanton CA, USA, Catalog # PA1466)
Host
Rabbit
Contents
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Clonality
Polyclonal
Isotype
Rabbit IgG
Immunogen
A synthetic peptide corresponding to a sequence at the C-terminus of mouse IL-2.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
No cross-reactivity with other proteins
Reactive Species
PA1466 is reactive to Il2 in Mouse
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Observed Molecular Weight
24 kDa
Calculated molecular weight
19400 MW
Background of IL-2
IL-2, Interleukin-2, formerly referred to as T-cell growth factor, is a powerfully immunoregulatory lymphokine that is produced by lectin-or antigen-activated T cells. In situ hybridization, the IL-2 gene is assigned to 4q26-q28. IL2 can act as a growth hormone for both B and T lymphocytes. It is useful in the study of the molecular nature of T-cell differentiation and, like interferons, augments natural killer cell activity.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
PA1466 is guaranteed for WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Western blot, 0.1-0.5μg/ml, Mouse
Validation Images & Assay Conditions
Click image to see more details
Anti-IL-2 antibody, PA1466, Western blotting
Lane 1: Recombinant Mouse IL-2 Protein 10ng
Lane 2: Recombinant Mouse IL-2 Protein 5ng
Lane 3: Recombinant Mouse IL-2 Protein 2.5ng
Protein Target Info & Infographic
Gene/Protein Information For Il2 (Source: Uniprot.org, NCBI)
Gene Name
Il2
Full Name
Interleukin-2
Weight
19400 MW
Superfamily
IL-2 family
Alternative Names
Interleukin-2;IL-2;T-cell growth factor;TCGF;Il2;Il-2; IL2 IL-2, TCGF, lymphokine interleukin 2 interleukin-2|T cell growth factor|aldesleukin|involved in regulation of T-cell clonal expansion
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on Il2, check out the Il2 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for Il2: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Interleukin-2 IL2 Antibody Picoband® (PA1466)
Hello CJ!
PA1466 has been cited in 8 publications:
*The publications in this section are manually curated by our staff scientists. They may differ from Bioz's machine gathered results. Both are accurate. If you find a publication citing this product but is missing from this list, please let us know we will issue you a thank-you coupon.
Positive effects of porcine IL-2 and IL-4 on virus-specific immune responses induced by the porcine reproductive and respiratory syndrome virus (PRRSV) %u2026
Women with Recurrent Miscarriage Have Decreased Expression of 25-Hydroxyvitamin D3-1?-Hydroxylase by the Fetal-Maternal Interface
Treatment of radiation-induced acute intestinal injury with bone marrow-derived mesenchymal stem cells
Zhong B, Shen H, Sun X, Wang H, Zhang Y, Sun Z. Cancer Biother Radiopharm. 2012 May;27(4):252-8. Doi: 10.1089/Cbr.2011.1105. Additive Effects Of Ulinastatin And Docetaxel On Growth Of Breast Cancer Xenograft In Nude Mice And Expression Of Pge2, Il...
Chen B, Liu L, Xu H, Yang Y, Zhang L, Zhang F. Exp Ther Med. 2015 Mar;9(3):1063-1067. Epub 2015 Jan 26. Effectiveness Of Immune Therapy Combined With Chemotherapy On The Immune Function And Recurrence Rate Of Cervical Cancer.
Gong T, Wang Cf, Yuan Jr, Li Y, Gu Jf, Zhao Bj, Zhang L, Jia Xb, Feng L, Liu Sl. Evid Based Complement Alternat Med. 2015;2015:630760. Doi: 10.1155/2015/630760. Epub 2015 May 3. Inhibition Of Tumor Growth And Immunomodulatory Effects Of Flavonoids...
Xie Ft, Cao Js, Zhao J, Yu Y, Qi F, Dai Xc. Transpl Immunol. 2015 Oct;33(2):69-77. Doi: 10.1016/J.Trim.2015.05.003. Epub 2015 May 20. Ido Expressing Dendritic Cells Suppress Allograft Rejection Of Small Bowel Transplantation In Mice By Expansion O...
Hu W,, Jing P, Wang L, Zhang Y, Yong J, Wang Y. Bmc Complement Altern Med. 2015 Apr 15;15:119. Doi: 10.1186/S12906-015-0642-3. The Positive Effects Of Ginsenoside Rg1 Upon The Hematopoietic Microenvironment In A D-Galactose-Induced Aged Rat Model.
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Customer Reviews
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Customer Q&As
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3 Customer Q&As for Anti-Interleukin-2 IL2 Antibody Picoband®
Question
We are currently using anti-IL2 antibody PA1466 for mouse tissue, and we are content with the WB results. The species of reactivity given in the datasheet says mouse. Is it possible that the antibody can work on horse tissues as well?
Verified Customer
Verified customer
Asked: 2020-01-08
Answer
The anti-IL2 antibody (PA1466) has not been tested for cross reactivity specifically with horse tissues, but there is a good chance of cross reactivity. We have an innovator award program that if you test this antibody and show it works in horse you can get your next antibody for free. Please contact me if I can help you with anything.
Boster Scientific Support
Answered: 2020-01-08
Question
We have observed staining in mouse blood. Do you have any suggestions? Is anti-IL2 antibody supposed to stain blood positively?
Verified Customer
Verified customer
Asked: 2019-11-14
Answer
From literature blood does express IL2. From Uniprot.org, IL2 is expressed in small intestine peyer's patch, placenta, blood, among other tissues. Regarding which tissues have IL2 expression, here are a few articles citing expression in various tissues:
Blood, Pubmed ID: 15489334
Placenta, Pubmed ID: 8824916
Boster Scientific Support
Answered: 2019-11-14
Question
We were happy with the WB result of your anti-IL2 antibody. However we have observed positive staining in small intestine peyer's patch secreted. using this antibody. Is that expected? Could you tell me where is IL2 supposed to be expressed?
Verified Customer
Verified customer
Asked: 2019-10-11
Answer
Based on literature, small intestine peyer's patch does express IL2. Generally IL2 expresses in secreted. Regarding which tissues have IL2 expression, here are a few articles citing expression in various tissues:
Blood, Pubmed ID: 15489334
Placenta, Pubmed ID: 8824916
Boster Scientific Support
Answered: 2019-10-11
