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Product Info Summary
| SKU: | A01311 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, IF, IHC-P, WB |
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Product info
Product Name
Anti-IL-17RA Antibody
View all IL-17RA/IL-17R Antibodies
SKU/Catalog Number
A01311
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-IL-17RA Antibody (Catalog # A01311). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
IL-17RA antibody can be stored at 4°C up to one year. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-IL-17RA Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A01311)
Host
Rabbit
Contents
IL-17RA Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
IL-17RA antibody was raised against an 18 amino acid peptide near the amino terminus of human IL-17RA. The immunogen is located within amino acids 150 - 200 of IL-17RA.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
IL-17RA antibody is human, mouse and rat reactive. Multiple isoforms of IL-17RA are known to exist. This antibody is predicted to not cross-react with other IL-17 receptor subunits.
Reactive Species
A01311 is reactive to IL17RA in Human, Mouse, Rat
Reconstitution
Observed Molecular Weight
68 kDa
Calculated molecular weight
96122 MW
Background of IL-17RA/IL-17R
Interleukin 17A (IL-17A) is a proinflammatory cytokine secreted by activated T-lymphocytes (1). It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. IL-17RA is a ubiquitous type I membrane glycoprotein that binds with low affinity to IL-17A and IL-17F (1,2). IL-17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis (3,4). Defects in IL-17RA are the cause of familial candidiasis type 5 (CANDF5) which is a rare disorder with altered immune responses and impaired clearance of fungal infections (5).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A01311 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
IL-17RA antibody can be used for detection of IL-17RA by Western blot at 1 - 2 μg/mL.
Antibody validated: Western Blot in mouse samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of IL17RA in A20 cell lysate with IL17RA antibody at 1 μg/mL.
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Immunohistochemistry of IL-17RA in human spleen tissue with IL-17RA antibody at 2.5 μg/ml.
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Immunofluorescence of IL-17RA in human spleen tissue with IL-17RA antibody at 20 μg/ml.
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Immunohistochemistry of IL-17RA in human spleen tissue with IL-17RA antibody at 2.5 μg/ml.
Protein Target Info & Infographic
Gene/Protein Information For IL17RA (Source: Uniprot.org, NCBI)
Gene Name
IL17RA
Full Name
Interleukin-17 receptor A
Weight
96122 MW
Alternative Names
CD217, IL17R, CANDF5, CDw217, IL-17RA, hIL-17R, Interleukin-17 receptor A, IL-17 receptor A Il17ra|AW538159, Cdw217, Il, Il17r, VDw21, VDw217|interleukin 17 receptor A|interleukin-17 receptor A|IL-17 receptor A|IL-17RA
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on IL17RA, check out the IL17RA Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for IL17RA: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-IL-17RA Antibody (A01311)
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