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Product Info Summary
| SKU: | M00531 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse |
| Host: | Mouse |
| Application: | Flow Cytometry, IP, ICC, WB |
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Product info
Product Name
Anti-Ikaros Purified IKZF1 Monoclonal Antibody
View all Ikaros/IKZF1 Antibodies
SKU/Catalog Number
M00531
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-Ikaros Purified IKZF1 Monoclonal Antibody (Catalog# M00531). Tested in Flow Cytometry, IP, WB, ICC application(s). This antibody reacts with Mouse, Human.
Storage & Handling
Store at 2-8°C. Do not freeze.
Cite This Product
Anti-Ikaros Purified IKZF1 Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M00531)
Host
Mouse
Contents
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Clonality
Monoclonal
Clone Number
4E9
Isotype
Mouse IgG1
Immunogen
Recombinant human Ikaros (C-terminal part). The mouse monoclonal antibody 4E9 recognizes Ikaros, a transcription factor (intracellular antigen) expressed broadly in hematopoietic progenitors and serving as a key regulator of lymphopoiesis.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
M00531 is reactive to IKZF1 in Human, Mouse
Reconstitution
Observed Molecular Weight
42 kDa
Calculated molecular weight
57528 MW
Background of Ikaros/IKZF1
Ikaros, also known as IKZF1 (Ikaros family zinc finger protein 1) is a hematopoietic-specific transcription factor involved in the regulation of lymphocyte development, together with other members of this family, such as Aiolos and Helios. Ikaros forms homo- and heterodimers with these proteins and functions predominantly in early hematopoietic development. Expression of Ikaros, Aiolos and Helios is restricted to cells of the hematopoietic system, whereas other family members, Eos and Pegassus, are more widely expressed. Disruption of Ikaros leads to T and B cell leukemias.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
M00531 is guaranteed for Flow Cytometry, IP, ICC, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Flow cytometry: 1-4 µg/ml. Intracellular staining.
Validation Images & Assay Conditions
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Protein Target Info & Infographic
Gene/Protein Information For IKZF1 (Source: Uniprot.org, NCBI)
Gene Name
IKZF1
Full Name
DNA-binding protein Ikaros
Weight
57528 MW
Superfamily
Ikaros C2H2-type zinc-finger protein family
Alternative Names
IKZF1; IK1; LYF1; LyF-1; IKAROS; PPP1R92; PRO0758; ZNFN1A1; Hs.54452; IKAROS family zinc finger 1; Lymphoid transcription factor LyF-1 IKZF1 CVID13, Hs.54452, IK1, IKAROS, LYF1, LyF-1, PPP1R92, PRO0758, ZNFN1A1 IKAROS family zinc finger 1 DNA-binding protein Ikaros|CLL-associated KW-6|ikaros family zinc finger protein 1|lymphoid transcription factor LyF-1|protein phosphatase 1, regulatory subunit 92|zinc finger protein, subfamily 1A, 1 (Ikaros)
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on IKZF1, check out the IKZF1 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for IKZF1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Ikaros Purified IKZF1 Monoclonal Antibody (M00531)
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