Anti-Mannose 6 Phosphate Receptor (Cation independent)/IGF2R Antibody Picoband®

IGF-II R/IGF2R antibody

Boster Bio Anti-Mannose 6 Phosphate Receptor (Cation independent)/IGF2R Antibody Picoband® catalog # A00951. Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance. Cited in 1 publication(s).

Product Info Summary

SKU: A00951
Size: 100 μg/vial
Reactive Species: Human, Mouse, Rat
Host: Rabbit
Application: ELISA, Flow Cytometry, IF, IHC, ICC, WB

Product Name

Anti-Mannose 6 Phosphate Receptor (Cation independent)/IGF2R Antibody Picoband®

View all IGF-II R/IGF2R Antibodies

SKU/Catalog Number

A00951

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-Mannose 6 Phosphate Receptor (Cation independent)/IGF2R Antibody Picoband® catalog # A00951. Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-Mannose 6 Phosphate Receptor (Cation independent)/IGF2R Antibody Picoband® (Boster Biological Technology, Pleasanton CA, USA, Catalog # A00951)

Host

Rabbit

Contents

Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

E. coli-derived human IGF2R recombinant protein (Position: F424-R529).

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross-reactivity with other proteins.

Reactive Species

A00951 is reactive to IGF2R in Human, Mouse, Rat

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Observed Molecular Weight

274 kDa

Calculated molecular weight

50408 MW

Background of IGF-II R/IGF2R

Insulin-like growth factor 2 receptor, also called IGF2R or I-MPR is a protein that in humans is encoded by the IGF2R gene. This gene is mapped to 6q25.3. This gene encodes a receptor for both insulin-like growth factor 2 and mannose 6-phosphate, although the binding sites for either are located on different segments of the receptor. This receptor functions in the intracellular trafficking of lysosomal enzymes, the activation of transforming growth factor beta, and the degradation of insulin-like growth factor 2. While the related mouse gene shows exclusive expression from the maternal allele, imprinting of the human gene appears to be polymorphic, with only a minority of individuals showing expression from the maternal allele.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

A00951 is guaranteed for ELISA, Flow Cytometry, IF, IHC, ICC, WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blot, 0.1-0.5μg/ml
Immunohistochemistry (Paraffin-embedded Section), 2-5μg/ml
Immunocytochemistry/Immunofluorescence, 5μg/ml
Flow Cytometry(Fixed), 1-3μg/1x106 cells
ELISA, 0.1-0.5μg/ml

Positive Control

WB: human Hela whole cell, human U87 whole cell, human HepG2 whole cell, rat heart tissue, rat PC-12 whole cell, mouse NIH/3T3 whole cell
IHC: human esophageal squamous carcinoma tissue, human liver cancer tissue, human lung cancer tissue, human ovarian cancer tissue
ICC/IF: A431 cell
FCM: HepG2 cell

Validation Images & Assay Conditions

Gene/Protein Information For IGF2R (Source: Uniprot.org, NCBI)

Gene Name

IGF2R

Full Name

Cation-independent mannose-6-phosphate receptor

Weight

50408 MW

Superfamily

MRL1/IGF2R family

Alternative Names

Cation-independent mannose-6-phosphate receptor; CI Man-6-P receptor; CI-MPR; M6PR; 300 kDa mannose 6-phosphate receptor; MPR 300; Insulin-like growth factor 2 receptor; Insulin-like growth factor II receptor; IGF-II receptor; M6P/IGF2 receptor; M6P/IGF2R; CD222; IGF2R; MPRI IGF2R CD222, CI-M6PR, CIMPR, M6P-R, M6P/IGF2R, MPR 300, MPR1, MPR300, MPRI insulin like growth factor 2 receptor cation-independent mannose-6-phosphate receptor|300 kDa mannose 6-phosphate receptor|CI Man-6-P receptor|IGF-II receptor|M6P/IGF2 receptor|insulin-like growth factor II receptor

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on IGF2R, check out the IGF2R Infographic

IGF2R infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for IGF2R: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

Hello CJ!

A00951 has been cited in 1 publications:

*The publications in this section are manually curated by our staff scientists. They may differ from Bioz's machine gathered results. Both are accurate. If you find a publication citing this product but is missing from this list, please let us know we will issue you a thank-you coupon.

Insulin-like growth factors in endometrioid adenocarcinoma: Correlation with clinico-pathological features and estrogen receptor expression

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Order DetailsPrice
A00951

100μg

$370
A00951-10ug

10μg sample (liquid)

$99
A00951-Biotin

100 μg Biotin conjugated

$570
A00951-Cy3

100 μg Cy3 conjugated

$570
A00951-Dylight488

100 μg Dylight488 conjugated

$570
A00951-Dylight550

100 μg Dylight550 conjugated

$570
A00951-Dylight594

100 μg Dylight594 conjugated

$570
A00951-FITC

100 μg FITC conjugated

$570
A00951-HRP

100 μg HRP conjugated

$570
A00951-APC

100 μg APC conjugated

$670
A00951-PE

100 μg PE conjugated

$670
A00951-iFluor647

100 μg iFluor647 conjugated

$670
A00951-carrier-free

Carrier Free

$370

More conjugates/formats

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A00951
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$370.00

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