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Product Info Summary
| SKU: | A02633 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, IF, ICC, WB |
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Product info
Product Name
Anti-IFITM1 Antibody
SKU/Catalog Number
A02633
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-IFITM1 Antibody (Catalog # A02633). Tested in ELISA, WB, ICC, IF applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
IFITM1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-IFITM1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A02633)
Host
Rabbit
Contents
IFITM1 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
IFITM1 antibody was raised against a 16 amino acid synthetic peptide near the center of human IFITM1. The immunogen is located within amino acids 40 - 90 of IFITM1.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
Depending on cell lines or tissues used, either full-length or other cleavage products may be observed.
Reactive Species
A02633 is reactive to IFITM1 in Human, Mouse, Rat
Reconstitution
Observed Molecular Weight
68 kDa
Calculated molecular weight
13964 MW
Background of IFITM1
IFITM1 (Interferon inducible transmembrane protein 1) is a member of the IFN-inducible transmembrane protein family. It is an essential mediator of interferon-gamma-induced antiproliferation and plays a role in the control of cell growth. IFITM1 is upregulated in several tumor types and may be useful as a tumor biomarker. Both mouse IFITM1 and IFITM3 are expressed on the cell surfaces of primordial germ cells in a developmentally-regulated manner. IFITM1 activity is required for primordial germ cell transit, and IFITM1 acts as a repulsive molecule by repelling non-IFITM1-expressing primordial germ cells from the mesoderm into the endoderm.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A02633 is guaranteed for ELISA, IF, ICC, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
IFITM1 antibody can be used for detection of IFITM1 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunocytochemistry starting at 20 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in mouse samples; Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of IFITM1 in 3T3 cell lysate with IFITM1 antibody at (A) 1 and (B) 2 μg/mL.
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Immunocytochemistry of IFITM1 in Jurkat cells with IFITM1 antibody at 20 μg/mL.
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Immunofluorescence of IFITM1 in Jurkat cells with IFITM1 antibody at 20 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For IFITM1 (Source: Uniprot.org, NCBI)
Gene Name
IFITM1
Full Name
Interferon-induced transmembrane protein 1
Weight
13964 MW
Superfamily
CD225/Dispanin family
Alternative Names
9-27, CD225, IFI17, LEU13, DSPA2a, Interferon-induced transmembrane protein 1, Dispanin subfamily A member 2a IFITM1 9-27, CD225, DSPA2a, IFI17, LEU13 interferon induced transmembrane protein 1 interferon-induced transmembrane protein 1|dispanin subfamily A member 2a|interferon-induced protein 17|interferon-inducible protein 9-27|leu-13
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on IFITM1, check out the IFITM1 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for IFITM1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-IFITM1 Antibody (A02633)
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