IFITM1 Antibodies

Interferon-induced transmembrane protein 1 (IFITM1)

IFN-induced antiviral protein that inhibits the entry of viruses into the host cell cytoplasm, allowing endocytosis, but preventing subsequent viral fusion and release of viral contents into the cytosol. Active against multiple viruses, including influenza A virus, SARS coronavirus (SARS-CoV), Marburg virus (MARV), Ebola virus (EBOV), Dengue virus (DNV), West Nile virus (WNV), human immunodeficiency virus type 1 (HIV-1) and hepatitis C virus (HCV).

Can inhibit: influenza virus hemagglutinin protein- mediated viral entry, MARV and EBOV GP1,2-mediated viral entry and SARS-CoV S protein-mediated viral entry. Also implicated in cell adhesion and control of cell growth and migration.

Gene Information

Human
Gene Name:	IFITM1
Uniprot:	P13164
Entrez:	8519

Family

Belongs to:
CD225/Dispanin family

Alternative Names

CD225 antigen; CD225; CD225Leu-13 antigen; IFI17; IFI17LEU13,9-27; IFITM1; interferon induced transmembrane protein 1 (9-27); Interferon-induced protein 17; interferon-induced transmembrane protein 1; Interferon-inducible protein 9-27; Leu-13

Molecular Weight

Mass (kDA):
13.964 kDA

Genomic Context

Human
Location:	11p15.5
Sequence:	11; NC_000011.10 (314040..315272)

Tissue Specificity

Bone (at protein level). Levels greatly elevated in colon cancer, cervical cancer, esophageal cancer and ovarian cancer. Expressed in glioma cell lines.

Subcellular Localizations

Cell membrane; Single-pass membrane protein.

Diseases

• Malignant Neoplasms
• Neoplasms
• Carcinoma
• Tissue Adhesions
• Virus Diseases
• Malignant Squamous Cell Neoplasm
• Adenocarcinoma
• Hepatitis
• Colorectal Cancer
• Cell Invasion
• Neoplasm Metastasis
• Carcinogenesis
• Influenza

• Malignant Neoplasm Of Stomach
• Neoplasm Invasiveness
• Hepatitis C
• Cell Transformation, Neoplastic
• Polyps
• Esophageal Neoplasms
• Hepatitis, Chronic

Pathways

• Pathogenesis
• Cell Adhesion
• Immune Response
• Cell Cycle
• Localization
• Cell Proliferation
• Germ Cell Development
• Cell Development
• Cell Differentiation
• Secretion
• Transport
• Virulence
• Reverse Transcription

• Viral Replication
• Cell Migration
• Osteoblast Differentiation
• Platelet Activation
• Tropism
• Biosynthetic Process
• Response To Paclitaxel

PTMs

• Phosphorylation
• Demethylation

• Acetylation
• Methylation

Research Areas

• Cell Cycle and Replication

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/IFITM1

Best Uses Of The IFITM1 Marker

To maximize the benefits of Boster Bio, read our Boster Bio Optimization Guides. These guides will help you select the right parameters and optimize your experiments to maximize results, and ensure you get the best results. Every experiment has problems and the troubleshooting guide in these guides will help you pinpoint and eliminate common sources of error. For more information about Boster Bio, check out the Boster Bio website. The website contains extensive articles on a wide variety of biomarker applications, from optimizing tests to troubleshooting.

Boster Bio

There are a variety of sources for antibodies for IFITM1. The top quality antibodies come with multiple platforms for validation, including human samples. Boster bio Anti IFITM1 antibody comes in a variety of formats that include IP and WB. The synthetic peptide it is made from reacts strongly with the IFITM1 protein. This antibody can be used in a wide variety of research applications, including cell culture, immunohistochemistry, and immunohistochemistry.

Boster Bio Anti-IFITM1 Marker

The Boster Bio Anti-IFITM1 marker is a monoclonal antibody that recognizes human IFITM1. This product reacts with primary antibodies as well as secondary antibodies. The Boster Bio Anti IFITM1 Marker is supplied in a lyophilized form and has been tested in WB, ICC, and IHC. Boster Bio Anti-IFITM1 marker contains a synthetic protein with molecular weight of around 5 micrograms.

Boster Bio optimization guides

If you're looking to improve your experiments with the IFITM1 marker, it is recommended to check out a manual that takes the IFITM1 gene as its main point of reference. This guide is packed with detailed information on how to fix the problem, embed and retrieve samples. These guides also offer troubleshooting tips for common issues. For additional support, Boster offers comprehensive technical information, blogs, and information about diseases.

Boster Bio troubleshooting guides

Researchers are faced with a variety of challenges they can face when performing experiments using Boster Bio equipment. Unexpected staining, weak signal, and a high background are all common problems. While many of the sources of error can be eliminated using proper controls, it is still possible to experience problems while using the instrument. Boster Bio has troubleshooting guides which can assist you. Continue reading to learn more about how to optimize your experiments using Boster Bio equipment.

A guide to Immunohistochemistry includes a step-by-step IHC protocol with illustrations and recommended reagents. Quality staining requires preparation of samples. The guide offers information on the best ways to go about preparing different types of preserved tissues. The guide also explains the best methods for preparing and embed different kinds of tissues. High-quality staining requires preparation of tissue.