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Product Info Summary
| SKU: | A03920 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human |
| Host: | Rabbit |
| Application: | ELISA, IHC-P, WB |
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Product info
Product Name
Anti-IFIT3 Antibody
SKU/Catalog Number
A03920
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-IFIT3 Antibody (Catalog # A03920). Tested in ELISA, WB, IHC-P applications. This antibody reacts with Human.
Storage & Handling
IFIT3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Cite This Product
Anti-IFIT3 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A03920)
Host
Rabbit
Contents
IFIT3 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
IFIT3 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human IFIT3. The immunogen is located within amino acids 380 - 430 of IFIT3 .
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
IFIT3 antibody is human specific. This antibody is predicted to not cross-react with other members of the IFIT protein family.
Reactive Species
A03920 is reactive to IFIT3 in Human
Reconstitution
Observed Molecular Weight
68 kDa
Calculated molecular weight
55985 MW
Background of IFIT3
The interferon-induced protein with tetratricopeptide repeats 3 (IFIT3) protein is a member of a family of tetratricopeptide repeat-containing proteins whose transcription is upregulated by interferons, virus infection, and molecular patterns such as dsRNA or lipopolysaccharides (1,2). These proteins have been suggested to induce anti-viral cellular activities in response to infection (2). IFIT3 has been shown to interact with TBK1 following RNA virus infection, thereby bridging TBK1 to VISA on the mitochondrion and activating IRF3 and thus the immune response (3).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A03920 is guaranteed for ELISA, IHC-P, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
IFIT3 antibody can be used for detection of IFIT3 by Western blot at 1 - 2 μg/ml. Antibody can also be used for Immunohistochemistry at 5 μg/mL.
Antibody validated: Western Blot in human samples and Immunohistochemistry in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of IFIT3 in HepG2 cell lysate with IFIT3 antibody at 1 μg/ml.
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Immunohistochemistry of IFIT3 in human liver tissue with IFIT3 antibody at 5 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For IFIT3 (Source: Uniprot.org, NCBI)
Gene Name
IFIT3
Full Name
Interferon-induced protein with tetratricopeptide repeats 3
Weight
55985 MW
Superfamily
IFIT family
Alternative Names
P60, IRG2, IFI60, IFIT4, ISG60, RIG-G, CIG-49, GARG-49, Interferon-induced protein with tetratricopeptide repeats 3, CIG49, IFIT-3 IFIT3 CIG-49, GARG-49, IFI60, IFIT4, IRG2, ISG60, P60, RIG-G, cig41 interferon induced protein with tetratricopeptide repeats 3 interferon-induced protein with tetratricopeptide repeats 3|CIG49|IFI-60K|IFIT-3|IFIT-4|ISG-60|interferon-induced 60 kDa protein|interferon-induced protein with tetratricopeptide repeats 4|retinoic acid-induced gene G protein
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on IFIT3, check out the IFIT3 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for IFIT3: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-IFIT3 Antibody (A03920)
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