Anti-ICOS ligand ICOSLG Antibody

Product Name

Anti-ICOS ligand ICOSLG Antibody

View all B7-H2/ICOSLG Antibodies

SKU/Catalog Number

A01965

Size

0.1 mg

Form

Liquid

Description

Boster Bio Anti-ICOS ligand ICOSLG Antibody (Catalog # A01965). Tested in ELISA, WB, IHC, IF applications. This antibody reacts with Human.

Storage & Handling

ICOSLG antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Cite This Product

Anti-ICOS ligand ICOSLG Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A01965)

Host

Rabbit

Contents

ICOSLG Antibody is supplied in PBS containing 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Immunogen

ICOSLG antibody was raised against a peptide corresponding to 17 amino acids near the center of human ICOSLG. The immunogen is located within amino acids 150 - 200 of ICOSLG.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

SRPK1 antibody is human, mouse and rat reactive. Multiple isoforms of SRPK1 are known to exist; this antibody will detect all except isoforms b and e. SRPK1 antibody is predicted to not cross-react with SRPK2.

Reactive Species

A01965 is reactive to ICOSLG in Human

Reconstitution

Observed Molecular Weight

68 kDa

Calculated molecular weight

33349 MW

Background of B7-H2/ICOSLG

Inhibitor of apoptosis proteins (IAPs) were initially identified in baculoviruses as proteins that inhibit apoptosis of the host cells to allow time for viral replication. Cellular homologues containing at least one baculoviral IAP repeat (BIR) motif essential for their anti-apoptosis activity have been identified in yeasts and higher organisms and often act by binding and inhibiting processed caspases. The activity of these proteins can be modulated by the expression of proteins such as Smac/DIABLO and XAF-1 which displace or prevent the binding of caspases by IAPs. Recently, a mitochondrial serine protease termed Omi/HtrA2 has been found to bind IAPs. Similar to Smac, Omi possesses a conserved IAP-binding motif, but acts to cleave IAPs to irreversibly inactivate IAPs and promote apoptosis.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

View more details

Applications

A01965 is guaranteed for ELISA, IF, IHC, WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

ICOSLG antibody can be used for Western blot at 1 μg/mL. Antibody can also be used for Immunohistochemistry at 2 μg/mL. For Immunoflorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.

Validation Images & Assay Conditions

Gene/Protein Information For ICOSLG (Source: Uniprot.org, NCBI)

Alternative Names

GL50, Inducible T Cell Costimulator Ligand, B7-Related Protein, B7 Homolog, Inducible T-Cell Costimulator Ligand, B7-Like Protein Gl50, B7 Homologue, B7RP-1, ICOSL, B7-H2, B7RP1, B7H2, Transmembrane Protein B7-H2 ICOS Ligand, Inducible T-Cell Co-Stimulator Ligand, CD275 Antigen, ICOS Ligand, KIAA0653, ICOS-L, CD275, LICOS ICOSLG B7-H2, B7H2, B7RP-1, B7RP1, B7h, CD275, GL50, ICOS-L, ICOSL, LICOS inducible T cell costimulator ligand ICOS ligand|B7 homolog 2|B7 homologue 2|B7-like protein Gl50|B7-related protein 1|transmembrane protein B7-H2 ICOS ligand

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

Here are featured tools and databases that you might find useful.

• Boster's Pathways Library
• Protein Databases
• Bioscience Research Protocol Resources
• Data Processing & Analysis Software
• Photo Editing Software
• Scientific Literature Resources
• Research Paper Management Tools
• Molecular Biology Software
• Primer Design Tools
• Bioinformatics Tools
• Phylogenetic Tree Analysis