ICOS ligand Antibodies

AND ICOSLG ELISA kits, ICOS ligand Proteins

Many biological assays use antibodies to detect ICOS ligand, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ICOS ligand in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ICOS ligand antibodies...

We validate the specificity of these antibodies to ICOS ligand by testing them on tissues known to express ICOSLG positively and negatively. Browse below to find the ICOSLG antibody that suites your experiment. We have 8 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ICOSLG Infographic by Boster Bio

All ICOSLG Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Mouse B7-H2 Recombinant Protein

Cell Culture

$360
Cat # R01965
5 µg/vial

Anti-ICOS ligand ICOSLG Antibody

Human

ELISA, IF, IHC, WB

$449
Cat # A01965
0.1 mg

Anti-ICOS ligand ICOSLG Antibody

Human, Mouse, Rat

IHC, WB

$405
Cat # A01965-1
100ul

ICOS Ligand (ICOSLG) (NM_015259) Human Recombinant Protein

$1249
Cat # PROTO75144
20 µg

Anti-ICOS Ligand (ICOSLG) Mouse Monoclonal Antibody [Clone ID: OTI2C5]

Human

IHC, WB

$523
Cat # M01965
100 µl

ICOS Ligand (ICOSLG) (NM_015259) Human Over-expression Lysate

Human

$628
Cat # LS023308
100 µg

Human B7-H2/ICOSL ELISA Kit PicoKine®

Human

ELISA

$499
Cat # EK2217
96 wells/kit, with removable strips.

Anti-CD275 Rabbit Monoclonal Antibody

Human

$370
Cat # M01965-1
100 µl/vial

ICOSLG Overview

Facts about ICOS ligand.

ICOSLG 3D structure. Source: alphafold

ICOS ligand (ICOSLG)

Ligand for the T-cell-specific cell surface receptor ICOS. Acts as a costimulatory signal for T-cell proliferation and cytokine secretion; induces also B-cell proliferation and differentiation into plasma cells.

Could play an significant role in mediating local tissue responses to inflammatory conditions, as well as in modulating the secondary immune response by co- stimulating memory T-cell function (By similarity). .

Gene Information

Human
Gene Name:	ICOSLG
Uniprot:	O75144
Entrez:	23308

Family

Belongs to:

immunoglobulin superfamily

Alternative Names

B7H2; B7-H2; B7H2B7 homolog 2; B7-H2B7-related protein 1; B7RP-1; B7RP1B7-like protein Gl50; B7RP-1LICOS; CD275 antigen; CD275; GL50; GL50transmembrane protein B7-H2 ICOS ligand; ICOSL; ICOS-L; ICOSLG; inducible T-cell co-stimulator ligand; KIAA0653ICOS ligand

Molecular Weight

Mass (kDA):
33.349 kDA

Genomic Context


Human

Location:	21q22.3
Sequence:	21; NC_000021.9 (44216979..44240943, complement)

Tissue Specificity

Isoform 1 is widely expressed (brain, heart, kidney, liver, lung, pancreas, placenta, skeletal muscle, bone marrow, colon, ovary, prostate, testis, lymph nodes, leukocytes, spleen, thymus and tonsil), while isoform 2 is detected only in lymph nodes, leukocytes and spleen. Expressed on activated monocytes and dendritic cells.