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Product Info Summary
| SKU: | A01111-Dyl550 |
|---|---|
| Size: | 100 μg/vial |
| Reactive Species: | Human |
| Host: | Rabbit |
| Application: | Flow Cytometry |
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Product info
Product Name
Anti-Human PDE4D DyLight® 550 conjugated Antibody
View all Phosphodiesterase 4D Antibodies
SKU/Catalog Number
A01111-Dyl550
Size
100 μg/vial
Form
Liquid
Description
Boster Bio Anti-Human PDE4D DyLight® 550 conjugated Antibody catalog # A01111-Dyl550. Tested in Flow Cytometry applications. This antibody reacts with Human.
Storage & Handling
At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
Cite This Product
Anti-Human PDE4D DyLight® 550 conjugated Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A01111-Dyl550)
Host
Rabbit
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
Clonality
Polyclonal
Isotype
Rabbit IgG
Immunogen
E. coli-derived human PDE4D recombinant protein (Position: H466-Q709).
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
No cross-reactivity with other proteins.
Reactive Species
A01111-Dyl550 is reactive to PDE4D in Human
Reconstitution
Observed Molecular Weight
39 kDa
Calculated molecular weight
91.115kDa
Background of Phosphodiesterase 4D
cAMP-specific 3',5'-cyclic phosphodiesterase 4D is an enzyme that in humans is encoded by the PDE4D gene. This gene encodes one of four mammalian counterparts to the fruit fly 'dunce' gene. The encoded protein has 3',5'-cyclic-AMP phosphodiesterase activity and degrades cAMP, which acts as a signal transduction molecule in multiple cell types. This gene uses different promoters to generate multiple alternatively spliced transcript variants that encode functional proteins.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A01111-Dyl550 is guaranteed for Flow Cytometry Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Flow Cytometry (Fixed), 1-3μg/1x106 cells
Validation Images & Assay Conditions
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Boster Kit Box
Protein Target Info & Infographic
Gene/Protein Information For PDE4D (Source: Uniprot.org, NCBI)
Gene Name
PDE4D
Full Name
cAMP-specific 3',5'-cyclic phosphodiesterase 4D
Weight
91.115kDa
Superfamily
cyclic nucleotide phosphodiesterase family
Alternative Names
cAMP-specific 3',5'-cyclic phosphodiesterase 4D; DPDE3; PDE43; PDE4D; DPDE3 PDE4D ACRDYS2, DPDE3, HSPDE4D, PDE43N2, STRK1, PDE4D phosphodiesterase 4D cAMP-specific 3,5-cyclic phosphodiesterase 4D|cAMP-specific phosphodiesterase PDE4D6|phosphodiesterase 4D, cAMP-specific (phosphodiesterase E3 dunce homolog, Drosophila)|testicular tissue protein Li 136
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on PDE4D, check out the PDE4D Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for PDE4D: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Human PDE4D DyLight® 550 conjugated Antibody (A01111-Dyl550)
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Customer Q&As
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1 Customer Q&As for Anti-Human PDE4D DyLight® 550 conjugated Antibody
Question
We are currently using anti-Human PDE4D DyLight® 550 conjugated antibody A01111-Dyl550 for human tissue, and we are content with the Flow Cytometry results. The species of reactivity given in the datasheet says human. Is it likely that the antibody can work on dog tissues as well?
T. Li
Verified customer
Asked: 2020-01-07
Answer
The anti-Human PDE4D DyLight® 550 conjugated antibody (A01111-Dyl550) has not been tested for cross reactivity specifically with dog tissues, but there is a good chance of cross reactivity. We have an innovator award program that if you test this antibody and show it works in dog you can get your next antibody for free. Please contact me if I can help you with anything.
Boster Scientific Support
Answered: 2020-01-07
