Product Info Summary
SKU: | M03832 |
---|---|
Size: | 0.1 mg |
Reactive Species: | Human |
Host: | Mouse |
Application: | Flow Cytometry, IP, WB |
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Product info
Product Name
Anti-Hu CD108 Purified SEMA7A Monoclonal Antibody
View all Semaphorin 7A Antibodies
SKU/Catalog Number
M03832
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-Hu CD108 Purified SEMA7A Monoclonal Antibody (Catalog# M03832). Tested in Flow Cytometry, IP, WB application(s). This antibody reacts with Human.
Storage & Handling
Store at 2-8°C. Do not freeze.
Cite This Product
Anti-Hu CD108 Purified SEMA7A Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M03832)
Host
Mouse
Contents
Tris buffered saline (TBS), pH 8.0, 15 mM sodium azide
Clonality
Monoclonal
Clone Number
MEM-150
Isotype
Mouse IgM
Immunogen
HPB-ALL human T cell line. The antibody MEM-150 reacts with CD108 (JMH blood group antigen), a 80 kDa GPI-anchored extracellular glycoprotein expressed on various cell types including erythrocytes, lymphoblasts; at low levels it is present on circulating lymphocytes.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
This antibody does not cross-react with Thy-1.1 alloantigen.
Reactive Species
M03832 is reactive to SEMA7A in Human
Applications
M03832 is guaranteed for Flow Cytometry, IP, WB Boster Guarantee
Observed Molecular Weight
42 kDa
Calculated molecular weight
74824 MW
Background of Semaphorin 7A
CD108 (Sema7A) is a GPI-anchored semaphorin family member, which enhances central and peripheral axonal growth and is required for proper axon track formation during ebryogenesis. CD108 also regulates osteoclast differentiation and pre-osteoblastic cell migration, and in immune system affects cell proliferation, chemotaxis and cytokine release. On erythrocytes CD108 defines the JMH (John-Milton-Hagen) human blood group. CD108 signalizes through its receptors –; plexin C1 and beta1 integrins.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Flow cytometry: 4 μg/ml.
Western blotting: Non-reducing conditions.
Validation Images & Assay Conditions
Click image to see more details
Figure 1. Flow Cytometry validation of SEMA7A using Anti-Hu CD108 Purified SEMA7A Monoclonal Antibody (M03832).
Flow cytometry analysis (surface staining) of human peripheral blood with anti-human CD108 (MEM-150) purifiedProtein Target Info & Infographic
Gene/Protein Information For SEMA7A (Source: Uniprot.org, NCBI)
Gene Name
SEMA7A
Full Name
Semaphorin-7A
Weight
74824 MW
Superfamily
semaphorin family
Alternative Names
CD108 antigen; CD108; CD108MGC126696; CDw108; H-SEMA-K1; H-Sema-L; JMH blood group antigen; JMH; John-Milton-Hargen human blood group Ag; MGC126692; sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, (semaphorin)7A (JMH blood group); sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, (semaphorin)7A; sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, 7A; Sema K1; Sema L; Sema7A; SEMAK1; SEMAL; SEMALJohn Milton Hagen blood group H-Sema K1; Semaphorin 7A; semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group); semaphorin K1; semaphorin L; s SEMA7A CD108, CDw108, H-SEMA-K1, H-Sema-L, JMH, SEMAK1, SEMAL semaphorin 7A (John Milton Hagen blood group) semaphorin-7A|JMH blood group antigen|John Milton Hagen blood group H-Sema K1|john-Milton-Hargen human blood group Ag|sema K1|sema L|sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, (semaphorin) 7A (JMH blood group)|sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, 7A|semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)|semaphorin-K1|semaphorin-L
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on SEMA7A, check out the SEMA7A Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for SEMA7A: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Hu CD108 Purified SEMA7A Monoclonal Antibody (M03832)
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