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Product Info Summary
| SKU: | M03651 |
|---|---|
| Size: | 100 µg |
| Reactive Species: | Human |
| Host: | Mouse |
| Application: | FACS |
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Product info
Product Name
Anti-hCD50 Antibody (Monoclonal, 101-1D2)
View all ICAM-3/CD50 Antibodies
SKU/Catalog Number
M03651
Size
100 µg
Form
Liquid
Description
Boster Bio Anti-hCD50 Antibody (Monoclonal, 101-1D2) (Catalog# M03651). Tested in FACS application(s). This antibody reacts with Human.
Storage & Handling
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Cite This Product
Anti-hCD50 Antibody (Monoclonal, 101-1D2) (Boster Biological Technology, Pleasanton CA, USA, Catalog # M03651)
Host
Mouse
Contents
100 μg in 200 μl PBS containing 0.05% BSA and 0.05% sodium azide.
Clonality
Monoclonal
Clone Number
101-1D2
Isotype
IgG2a Kappa
Immunogen
Stimulated human leukocytes
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
Does not cross-react with primate, avian or amphibian GR.
Reactive Species
M03651 is reactive to ICAM3 in Human
Reconstitution
Reconstitute with distilled water.
Observed Molecular Weight
68 kDa
Calculated molecular weight
59541 MW
Background of ICAM-3/CD50
Recognizes a protein of 42-46kDa, identified as MAGE-1. This monoclonal antibody does not cross-react with MAGE-2, -3, -4, -6 -9, -10, -or -12 protein. Human malignant neoplasms carry rejection antigens that are recognized by the patients' autologous, tumor directed and specific, cytolytic, CD8+ T lymphocyte clones (CTL). The MAGE family of genes codes an important group of antigens. It was identified that melanomas and primary glial brain tumors express common melanoma associated antigens (MAAs). Because MAGE-1 is expressed on a significant proportion of human neoplasms of various histological types (melanoma, brain tumors of glial origin, neuroblastoma, non-small cell lung cancer, breast, gastric, colorectal, ovarian, renal cell carcinomas) and not on normal tissues, the encoded antigen may serve as a marker of early detection and target for cancer immunotherapy.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
M03651 is guaranteed for FACS Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
FACS: 1-2 µg/10^6 cells
Validation Images & Assay Conditions
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Cell Surface flow analysis of hCD50 in PBMC (Lymphocyte gated) using 1 &mu
Protein Target Info & Infographic
Gene/Protein Information For ICAM3 (Source: Uniprot.org, NCBI)
Gene Name
ICAM3
Full Name
Intercellular adhesion molecule 3
Weight
59541 MW
Superfamily
immunoglobulin superfamily
Alternative Names
Intercellular adhesion molecule 3;ICAM-3;CDw50;ICAM-R;CD50;ICAM3; ICAM3 CD50, CDW50, ICAM-R intercellular adhesion molecule 3 intercellular adhesion molecule 3|ICAM-3
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on ICAM3, check out the ICAM3 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for ICAM3: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-hCD50 Antibody (Monoclonal, 101-1D2) (M03651)
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No publications found for M03651
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