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Product Info Summary
| SKU: | A07110 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, IF, IHC-P, WB |
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Product info
Product Name
Anti-Guanylate-binding protein 5 GBP5 Antibody
SKU/Catalog Number
A07110
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-Guanylate-binding protein 5 GBP5 Antibody (Catalog # A07110). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
GBP5 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Cite This Product
Anti-Guanylate-binding protein 5 GBP5 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A07110)
Host
Rabbit
Contents
GBP5 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
GBP5 antibody was raised against a 16 amino acid peptide near the carboxy terminus of human GBP5 . The immunogen is located within the last 50 amino acids of GBP5.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
GBP5 antibody is predicted to not cross-react with other GBP family members.
Reactive Species
A07110 is reactive to GBP5 in Human, Mouse, Rat
Reconstitution
Observed Molecular Weight
68 kDa
Calculated molecular weight
66617 MW
Background of GBP5
The guanylate-binding proteins (GBPs) are a family of interferon-induced GTP-binding proteins function in innate immunity against microbial and viral pathogens. In humans, there are seven GBPs from hGBP1 to hGBP7. Human GBP1 and GBP2 have been shown to exhibit antiviral activity as well as being able to regulate the inhibition of proliferation and invasion of endothelial cells in response to interferon (IFN). GBP5 promotes selective NALP3 inflammasome responses to pathogenic bacteria and soluble but not crystalline inflammasome priming agents.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A07110 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
GBP5 Antibody can be used for detection of GBP5 by Western blot at 1 μg/mL.
Antibody validated: Western Blot in rat samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of GBP5 in rat liver tissue lysate with GBP5 antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.
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Immunohistochemistry of GBP5 in human liver tissue with GBP5 antibody at 2.5 μg/ml.
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Immunofluorescence of GBP5 in human liver tissue with GBP5 antibody at 20 μg/ml.
Protein Target Info & Infographic
Gene/Protein Information For GBP5 (Source: Uniprot.org, NCBI)
Gene Name
GBP5
Full Name
Guanylate-binding protein 5
Weight
66617 MW
Superfamily
TRAFAC class dynamin-like GTPase superfamily
Alternative Names
GBP-5, Guanylate-binding protein 5, GBP-TA antigen, GBP-5 GBP5 GBP-5 guanylate binding protein 5 guanylate-binding protein 5|GBP-TA |GTP-binding protein 5|guanine nucleotide-binding protein 5
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on GBP5, check out the GBP5 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for GBP5: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Guanylate-binding protein 5 GBP5 Antibody (A07110)
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