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GBP5 Antibodies
AND GBP5 ELISA kits, GBP5 Proteins
Many biological assays use antibodies to detect GBP5, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with GBP5 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop GBP5 antibodies...
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GBP5 Infographic by Boster Bio
All GBP5 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
ELISA, IF, IHC-P, WB
$449
Cat # A07110
0.1 mg
Cat # A07110
0.1 mg
Human, Monkey
Flow Cytometry, IF, WB
$523
Cat # M07110
100 µl
Cat # M07110
100 µl
GBP5 Overview
Facts about Guanylate-binding protein 5.
Guanylate-binding protein 5 (GBP5)
As an activator of NLRP3 inflammasome meeting, plays a role in innate immunity and inflammation. Promotes selective NLRP3 inflammasome meeting in response to microbial and soluble, but not crystalline, agents (PubMed:22461501).
Hydrolyzes GTP, but in contrast to other family members, doesn't create GMP (PubMed:20180847). .
Gene Information
| Human | |
|---|---|
| Gene Name: | GBP5 |
| Uniprot: | Q96PP8 |
| Entrez: | 115362 |
Family
| Belongs to: |
|---|
| TRAFAC class dynamin-like GTPase superfamily |
Alternative Names
GBP-5; GBP-TA antigen; GTP-binding protein 5; Guanine nucleotide-binding protein 5; guanylate binding protein 5; guanylate-binding protein 5
Molecular Weight
Mass (kDA):
66.617 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 1p22.2 |
| Sequence: | 1; NC_000001.11 (89258950..89272860, complement) |
Tissue Specificity
Expressed in peripheral blood monocytes (at protein level).
Subcellular Localizations
Cytoplasm. Golgi apparatus membrane; Lipid-anchor.
Diseases
- Melanoma
- Lymphoma
- Inflammation
- Infectious Mononucleosis
- Lymphoma, T-cell, Cutaneous
- Endometrial Polyp
- Malignant Neoplasm Of Urinary Bladder
- Carcinoma
- Superficial Bladder Cancer
- Tumor Angiogenesis
- Neoplasms
- Refractory Angina
Pathways
- Immune Response
- Secretion
- Transport
- Cell Proliferation
- Muscle Contraction
- Pyroptosis
- Virulence
- Macrophage Activation
- Decidualization
- Tissue Development
PTMs
- Prenylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GBP5
bosterbio.com/bosterbio-gene-info-cards/GBP5
References
PMID: 15175044 by Fellenberg F., et al. GBP-5 splicing variants: New guanylate-binding proteins with tumor- associated expression and antigenicity.
PMID: 17266443 by Tripal P., et al. Unique features of different members of the human guanylate-binding protein family.