Anti-GRASP Gripap1 Antibody

Product Name

Anti-GRASP Gripap1 Antibody

View all GRASP1 Antibodies

SKU/Catalog Number

A13005-1

Size

100 µl

Form

Liquid

Description

Boster Bio Anti-GRASP Gripap1 Antibody (Catalog # A13005-1). Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-GRASP Gripap1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A13005-1)

Host

Rabbit

Contents

Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Clonality

Polyclonal

Isotype

IgG

Immunogen

Peptide sequence around aa. 814-818(Q-E-I-V-R ) derived from Rat GRASP.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A13005-1 is reactive to Gripap1 in Human, Mouse, Rat

Applications

A13005-1 is guaranteed for WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

96074 MW

Background of GRASP1

GRASP (GRP1-associated scaffold protein, tamalin) is a 395 amino acid protein encoded by the human gene GRASP . GRASP is a scaffold protein that com-prises multiple protein-interacting domains, including a 95 kDa postsynaptic density protein (PSD-95)/discs-large/ZO-1 (PDZ) domain, a leucine-zipper region and a carboxyl-terminal PDZ-binding motif. GRASP is involved with intracellular trafficking and contributes to the macromolecular organization of group 1 metabotropic glutamate receptors (mGluRs) at synapses. GRASP forms a heteromer composed of GRASP , PSCD2 and at least one mGluR-1. It also interacts with PSCD3, mGluR-2, mGluR-3 and mGluR-5. GRASP is highly expressed in brain and has lower levels of expression in lung, heart, embryo, kidney and ovary.

Kitano, J., Kimura, K., Yamazaki, Y., Soda, T., Shigemoto, R., Nakajima, Y.and Nakanishi, S. 2002. Tamalin, J. Neurosci. 22: 280-1289.
Hall, B.S., Gabernet-Castello, C., Voak, A., Goulding, D., Natesan, S.K. and Field, M.C. 2006. J. Biol. Chem. 281: 27600-27612.
Sugi, T., Oyama, T., Muto, T., Nakanishi, S., Morikawa, K. and Jingami, H. 2007. Crystal structures of autoinhibitory PDZ domain of Tamalin EMBO J.26: 2192-2205.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Predicted MW: 95kd
Western blotting: 1:500~1:1000

Validation Images & Assay Conditions

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Western blot analysis of extracts from rat brain and mouse brain tissue using GRASP antibody A13005-1

Gene/Protein Information For Gripap1 (Source: Uniprot.org, NCBI)

Alternative Names

DKFZp434P0630; GRASP1; GRASP-1MGC126595; GRIP1 associated protein 1; GRIP1-associated protein 1; GRIPAP1; KIAA1167MGC126593; MPMGp800B12492Q3 Gripap1|AI854681, DXImx47, DXImx47e, GRA, GRASP-1, Sfc1, Sfc10, mKIAA1167|GRIP1 associated protein 1|GRIP1-associated protein 1|HCMV-interacting protein

For more info on Gripap1, check out the Gripap1 Infographic

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In this infographic, you will see the following information for Gripap1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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