Anti-Artemis (phospho-S516) DCLRE1C Antibody

Product Name

Anti-Artemis (phospho-S516) DCLRE1C Antibody

View all Artemis Antibodies

SKU/Catalog Number

A02405S516

Size

100ul

Form

Liquid

Description

Boster Bio Anti-Artemis (phospho-S516) DCLRE1C Antibody catalog # A02405S516. Tested in WB,IHC applications. This antibody reacts with Human,Mouse,Rat.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-Artemis (phospho-S516) DCLRE1C Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A02405S516)

Host

Rabbit

Contents

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from human Dvl-2

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A02405S516 is reactive to DCLRE1C in Human, Mouse, Rat

Applications

A02405S516 is guaranteed for IHC, WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

78436 MW

Background of Artemis

Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. The a and a' chains contain the catalytic site. Participates in Wnt signaling. CK2 phosphorylates 'Ser-392' of p53/TP53 following UV irradiation.

Keller D.M., Zeng X., et al., Mol. Cell 7:283-292(2001)
Keller D.M., Lu H. et al., J. Biol. Chem. 277:50206-50213(2002)
Trembley J.H., Tatsumi S., et al., Mol. Cell. Biol. 25:1446-1457(2005)
Niefind K., Guerra B., et al., Acta Crystallogr. D 56:1680-1684(2000)

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB: 1:500-1:1000
IHC: 1:50-1:200

Validation Images & Assay Conditions

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Figure 1. Western blotting validation for Anti-Artemis (phospho-S516) DCLRE1C Antibody A02405S516

Western blot (WB) analysis of p-Artemis (S516) polyclonal antibody at 1:500 dilution
Lane1:HEK293T cell lysate
Lane2:Mouse skeletal muscle tissue lysate
Lane3:Rat skeletal muscle tissue lysate
Electrophoresis was performed on a SDS-PAGE gel. To determine SDS-PAGE gel concentration

Gene/Protein Information For DCLRE1C (Source: Uniprot.org, NCBI)

Alternative Names

ASCID; DCLREC1C; DNA cross-link repair 1C protein; DNA cross-link repair 1C; EC 3.1; FLJ36438; hSNM1C; protein artemis; Protein A-SCID; PSO2 homolog; RS-SCID; severe combined immunodeficiency, type a (Athabascan); SNM1 homolog C; SNM1CS. cerevisiae); SNM1-like protein DCLRE1C A-SCID, DCLREC1C, RS-SCID, SCIDA, SNM1C DNA cross-link repair 1C protein artemis|DNA cross-link repair 1C (PSO2 homolog, S. cerevisiae)|SNM1 homolog C|SNM1-like protein|severe combined immunodeficiency, type a (Athabascan)

For more info on DCLRE1C, check out the DCLRE1C Infographic

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In this infographic, you will see the following information for DCLRE1C: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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