Anti-GNAS Antibody (N-Term)

Product Name

Anti-GNAS Antibody (N-Term)

View all G protein alpha Antibodies

SKU/Catalog Number

M01243

Size

50 µl

Description

Boster Bio Anti-GNAS Antibody (N-Term) (Catalog # M01243). Tested in WB application(s). This antibody reacts with Human, Mouse, Rat.

Storage & Handling

Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Cite This Product

Anti-GNAS Antibody (N-Term) (Boster Biological Technology, Pleasanton CA, USA, Catalog # M01243)

Host

Rabbit

Contents

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

This GNAS antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 51-83 amino acids from human GNAS.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

M01243 is reactive to GNAS in Human, Mouse, Rat

Applications

M01243 is guaranteed for WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

45665 Da

Background of G protein alpha

Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(s) protein is involved in hormonal regulation of adenylate cyclase: it activates the cyclase in response to beta-adrenergic stimuli. Stimulates the Ras signaling pathway via RAPGEF2.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB: 1:8000

Validation Images & Assay Conditions

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All lanes : Anti-GNAS Antibody (N-Term) at 1:8000 dilution
Lane 1: HepG2 whole cell lysate
Lane 2: Raji whole cell lysate
Lane 3: mouse brain lysate
Lane 4: rat brain lysate
Lane 5: human cerebellum lysate
Lysates/proteins at 20 µg per lane.
Secondary
Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution.
Predicted band size : 46 kDa
Blocking/Dilution buffer: 5% NFDM/TBST.

Gene/Protein Information For GNAS (Source: Uniprot.org, NCBI)

Alternative Names

Adenylate cyclase-stimulating G alpha protein; AHO; Alternative gene product encoded by XL-exon; Extra large alphas protein; GNAS complex locus; GNAS1GSA; GNASXL; GPSAC20orf45; GSP; guanine nucleotide binding protein (G protein), alpha stimulating activitypolypeptide 1; guanine nucleotide regulatory protein; guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas; MGC33735; NESP; NESP55; neuroendocrine secretory protein; PHP1A; PHP1B; PHP1C; POH; protein ALEX; SCG6; secretogranin VI; XLalphas GNAS AHO, C20orf451, GPSA, GSA, GSP, NESP, PITA3, POH, SCG6, SgVI, GNAS GNAS complex locus protein ALEX|protein GNAS|protein SCG6 (secretogranin VI)|G protein subunit alpha S|adenylate cyclase-stimulating G alpha protein|alternative gene product encoded by XL-exon|extra large alphas protein|guanine nucleotide binding protein (G protein), alpha stimulating activity polypeptide 1|guanine nucleotide regulatory protein|secretogranin VI

For more info on GNAS, check out the GNAS Infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for GNAS: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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