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Product Info Summary
| SKU: | M01243 |
|---|---|
| Size: | 50 µl |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | WB |
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Product info
Product Name
Anti-GNAS Antibody (N-Term)
View all G protein alpha Antibodies
SKU/Catalog Number
M01243
Size
50 µl
Description
Boster Bio Anti-GNAS Antibody (N-Term) (Catalog # M01243). Tested in WB application(s). This antibody reacts with Human, Mouse, Rat.
Storage & Handling
Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Cite This Product
Anti-GNAS Antibody (N-Term) (Boster Biological Technology, Pleasanton CA, USA, Catalog # M01243)
Host
Rabbit
Contents
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
Clonality
Polyclonal
Isotype
Rabbit IgG
Immunogen
This GNAS antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 51-83 amino acids from human GNAS.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
M01243 is reactive to GNAS in Human, Mouse, Rat
Reconstitution
Calculated molecular weight
45665 Da
Background of G protein alpha
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(s) protein is involved in hormonal regulation of adenylate cyclase: it activates the cyclase in response to beta-adrenergic stimuli. Stimulates the Ras signaling pathway via RAPGEF2.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
M01243 is guaranteed for WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:8000
Validation Images & Assay Conditions
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All lanes : Anti-GNAS Antibody (N-Term) at 1:8000 dilution
Lane 1: HepG2 whole cell lysate
Lane 2: Raji whole cell lysate
Lane 3: mouse brain lysate
Lane 4: rat brain lysate
Lane 5: human cerebellum lysate
Lysates/proteins at 20 µg per lane.
Secondary
Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution.
Predicted band size : 46 kDa
Blocking/Dilution buffer: 5% NFDM/TBST.
Protein Target Info & Infographic
Gene/Protein Information For GNAS (Source: Uniprot.org, NCBI)
Gene Name
GNAS
Full Name
Neuroendocrine secretory protein 55
Weight
45665 Da
Superfamily
NESP55 family
Alternative Names
Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, Adenylate cyclase-stimulating G alpha protein, GNAS, GNAS1, GSP GNAS AHO, C20orf451, GPSA, GSA, GSP, NESP, PITA3, POH, SCG6, SgVI, GNAS GNAS complex locus protein ALEX|protein GNAS|protein SCG6 (secretogranin VI)|G protein subunit alpha S|adenylate cyclase-stimulating G alpha protein|alternative gene product encoded by XL-exon|extra large alphas protein|guanine nucleotide binding protein (G protein), alpha stimulating activity polypeptide 1|guanine nucleotide regulatory protein|secretogranin VI
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on GNAS, check out the GNAS Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for GNAS: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-GNAS Antibody (N-Term) (M01243)
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