Anti-GDNF Antibody Picoband®

GDNF antibody

Boster Bio Anti-GDNF Antibody catalog # PA1465. Tested in IHC, WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance. Cited in 7 publication(s).

Product Info Summary

SKU: PA1465
Size: 100 μg/vial
Reactive Species: Human, Rat
Host: Rabbit
Application: IHC, WB

Product Name

Anti-GDNF Antibody Picoband®

View all GDNF Antibodies

SKU/Catalog Number

PA1465

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-GDNF Antibody catalog # PA1465. Tested in IHC, WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-GDNF Antibody Picoband® (Boster Biological Technology, Pleasanton CA, USA, Catalog # PA1465)

Host

Rabbit

Contents

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

A synthetic peptide corresponding to a sequence in the middle region of human GDNF, different from the related mouse sequence by three amino acids and rat sequence by two amino acids.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross-reactivity with other proteins

Reactive Species

PA1465 is reactive to GDNF in Human, Rat

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Observed Molecular Weight

24 kDa

Calculated molecular weight

23720 MW

Background of GDNF

GDNF, Glial cell-derived neurotrophic factor, is a protein that, in humans, is encoded by the GDNF gene. GDNF is a small protein that potently promotes the survival of many types of neurons. GDNF is a founding member of the GDNF family of ligands (GFL). The GDNF gene is mapped to human chromosome 5p13.1-p12 by fluorescence in situ hybridization (FISH). This gene encodes a highly conserved neurotrophic factor. The recombinant form of this protein was shown to promote the survival and differentiation of dopaminergic neurons in culture, and was able to prevent apoptosisof motor neurons induced by axotomy. The encoded protein is processed to a mature secreted form that exists as a homodimer. The mature form of the protein is a ligand for the product of the RET (rearranged during transfection) protooncogene.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

PA1465 is guaranteed for IHC, WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blot, 0.1-0.5μg/ml, Human
Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml, Human, Rat, By Heat

Positive Control

IHC: Rat Brain Tissue, Human Lung Cancer Tissue

Validation Images & Assay Conditions

Gene/Protein Information For GDNF (Source: Uniprot.org, NCBI)

Gene Name

GDNF

Full Name

Glial cell line-derived neurotrophic factor

Weight

23720 MW

Superfamily

TGF-beta family

Alternative Names

Glial cell line-derived neurotrophic factor;hGDNF;Astrocyte-derived trophic factor;ATF;GDNF; GDNF ATF, ATF1, ATF2, HFB1-GDNF, HSCR3 glial cell derived neurotrophic factor glial cell line-derived neurotrophic factor|astrocyte-derived trophic factor

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on GDNF, check out the GDNF Infographic

GDNF infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for GDNF: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

Hello CJ!

PA1465 has been cited in 7 publications:

*The publications in this section are manually curated by our staff scientists. They may differ from Bioz's machine gathered results. Both are accurate. If you find a publication citing this product but is missing from this list, please let us know we will issue you a thank-you coupon.

Antenatal taurine reduces cerebral cell apoptosis in fetal rats with intrauterine growth restriction

The interplay of BDNF-TrkB with NMDA receptor in propofol-induced cognition dysfunction

Culture bovine prospermatogonia with 2i medium

Surface functionalization of TiO2 nanotubes with minocycline and its in vitro biological effects on Schwann cells

Antenatal taurine reduces cerebral cell apoptosis in fetal rats with intrauterine growth restriction

Li R, Xia W, Zhang Z, Wu K. Plos One. 2011;6(6):E21663. Doi: 10.1371/Journal.Pone.0021663. Epub 2011 Jun 27. S100B Protein, Brain-Derived Neurotrophic Factor, And Glial Cell Line-Derived Neurotrophic Factor In Human Milk.

Zhang X, Shi K, Li Y, Zhang H, Hao J. Reprod Toxicol. 2014 Jun;45:87-93. Doi: 10.1016/J.Reprotox.2014.01.009. Epub 2014 Feb 4. Lipopolysaccharide Inhibits The Self-Renewal Of Spermatogonial Stem Cells In Vitro Via Downregulation Of Gdnf Expression...

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3 Customer Q&As for Anti-GDNF Antibody Picoband®

Question

Is PA1465 suitable for ICC?

Verified customer

Asked: 2020-03-10

Answer

The Anti-GDNF Antibody PA1465 is not suitable for Immunocytochemistry.

Boster Scientific Support

Answered: 2020-03-10

Question

Is PA1465 able to detect preGDNF and mature GDNF?

Verified Customer

Verified customer

Asked: 2019-10-16

Answer

PA1465 is only able to detect mature GDNF

Boster Scientific Support

Answered: 2019-10-16

Question

Can PA1465 be used to detect GDNF in human testicular tissue?

Verified customer

Asked: 2019-03-26

Answer

Test result of the Anti-GDNF Antibody (PA1465) in human testicular tissue is not good. We do not recommend using PA1465 to test human testicular tissues.

Boster Scientific Support

Answered: 2019-04-01

Order DetailsPrice
PA1465

100μg

$370
PA1465-10ug

10μg sample (liquid)

$99
PA1465-Biotin

100 μg Biotin conjugated

$570
PA1465-Cy3

100 μg Cy3 conjugated

$570
PA1465-Dylight488

100 μg Dylight488 conjugated

$570
PA1465-Dylight550

100 μg Dylight550 conjugated

$570
PA1465-Dylight594

100 μg Dylight594 conjugated

$570
PA1465-FITC

100 μg FITC conjugated

$570
PA1465-HRP

100 μg HRP conjugated

$570
PA1465-APC

100 μg APC conjugated

$670
PA1465-PE

100 μg PE conjugated

$670
PA1465-iFluor647

100 μg iFluor647 conjugated

$670
PA1465-carrier-free

Carrier Free

$370

More conjugates/formats

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PA1465
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$370.00

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