Anti-FOLR2 Antibody

Product Name

Anti-FOLR2 Antibody

View all FOLR2 Antibodies

SKU/Catalog Number

M04574-1

Size

50 µl

Description

Boster Bio Anti-FOLR2 Antibody (Catalog # M04574-1). Tested in WB application(s). This antibody reacts with Human.

Storage & Handling

Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Cite This Product

Anti-FOLR2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M04574-1)

Host

Mouse

Contents

Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

Clonality

Monoclonal

Clone Number

1905CT501.41.76

Isotype

IgG2b,κ

Immunogen

This FOLR2 antibody is generated from a mouse immunized with a recombiant protein from human FOLR2.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

M04574-1 is reactive to FOLR2 in Human

Applications

M04574-1 is guaranteed for WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

29280 Da

Background of FOLR2

Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into the interior of cells. Has high affinity for folate and folic acid analogs at neutral pH. Exposure to slightly acidic pH after receptor endocytosis triggers a conformation change that strongly reduces its affinity for folates and mediates their release.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB: 1:1000-1:2000

Validation Images & Assay Conditions

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All lanes : Anti-FOLR2 Antibody at 1:1000-1:2000 dilution
Lane 1: Human spleen lysate
Lane 2: Human placenta lysate
Lysates/proteins at 20 µg per lane.
Secondary
Goat Anti-mouse IgG, (H+L), Peroxidase conjugated at 1/10000 dilution.
Predicted band size : 29 kDa
Blocking/Dilution buffer: 5% NFDM/TBST.

Gene/Protein Information For FOLR2 (Source: Uniprot.org, NCBI)

Alternative Names

beta-HFR; FBP; FBP/PL-1; folate receptor 2 (fetal); Folate receptor 2; folate receptor beta; folate receptor, beta; Folate receptor, fetal/placental; folate-binding protein, fetal/placental; FOLR2; FR-beta; FR-P3; Placental folate-binding protein FOLR2 BETA-HFR, FBP, FBP/PL-1, FOLR1, FR-BETA, FR-P3, FRbeta folate receptor beta folate receptor beta|folate receptor 2 (fetal)|folate receptor alpha|folate receptor, fetal/placental|folate-binding protein, fetal/placental|placental folate-binding protein

For more info on FOLR2, check out the FOLR2 Infographic

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In this infographic, you will see the following information for FOLR2: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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