Anti-FIR FARP2 Antibody

Product Name

Anti-FIR FARP2 Antibody

View all FARP2 Antibodies

SKU/Catalog Number

A08176

Size

100 µl

Form

Liquid

Description

Boster Bio Anti-FIR FARP2 Antibody (Catalog # A08176). Tested in WB applications. This antibody reacts with Human, Mouse.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-FIR FARP2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A08176)

Host

Rabbit

Contents

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from Internal of human FIR.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A08176 is reactive to FARP2 in Human, Mouse

Reconstitution

Calculated molecular weight

119888 MW

Background of FARP2

Functions as guanine nucleotide exchange factor that activates RAC1. May have relatively low activity. Plays a role in the response to class 3 semaphorins and remodeling of the actin cytoskeleton. Plays a role in TNFSF11-mediated osteoclast differentiation, especially in podosome rearrangement and reorganization of the actin cytoskeleton. Regulates the activation of ITGB3, integrin signaling and cell adhesion By similarity.

Nagase T., DNA Res. 5:31-39(1998).
The MGC Project Team, Genome Res. 14:2121-2127(2004).
Jandrig B., Oncogene 23:9295-9302(2004).

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

A08176 is guaranteed for WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blotting: 1:500~1:3000

Validation Images & Assay Conditions

Gene/Protein Information For FARP2 (Source: Uniprot.org, NCBI)

Alternative Names

FERM, RhoGEF and pleckstrin domain-containing protein 2;FERM domain including RhoGEF;FIR;Pleckstrin homology domain-containing family C member 3;PH domain-containing family C member 3;FARP2;KIAA0793, PLEKHC3; FARP2 FIR, FRG, PLEKHC3 FERM, ARH/RhoGEF and pleckstrin domain protein 2 FERM, ARHGEF and pleckstrin domain-containing protein 2|FERM domain including RhoGEF|FERM, RhoGEF and pleckstrin domain protein 2|FERM, RhoGEF and pleckstrin domain-containing protein 2|FGD1-related Cdc42-GEF|PH domain-containing family C member 3|pleckstrin homology domain-containing family C member 3

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

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