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- Table of Contents
Facts about FERM, ARHGEF and pleckstrin domain-containing protein 2.
Plays a role in the response to class 3 semaphorins and remodeling of the actin cytoskeleton. Plays a role in TNFSF11-mediated osteoclast differentiation, especially in podosome rearrangement and reorganization of the actin cytoskeleton.
Human | |
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Gene Name: | FARP2 |
Uniprot: | O94887 |
Entrez: | 9855 |
Belongs to: |
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No superfamily |
FERM, RhoGEF and pleckstrin domain protein 2; FGD1-related Cdc42-GEF; FIRFERM domain including RhoGEF; FRG; KIAA0793PH domain-containing family C member 3; Pleckstrin homology domain-containing family C member 3; PLEKHC3FERM, RhoGEF and pleckstrin domain-containing protein 2
Mass (kDA):
119.888 kDA
Human | |
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Location: | 2q37.3 |
Sequence: | 2; NC_000002.12 (241356285..241494841) |
PMID: 9872452 by Nagase T., et al. Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.
PMID: 14702039 by Ota T., et al. Complete sequencing and characterization of 21,243 full-length human cDNAs.