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Product Info Summary
| SKU: | PA1690 |
|---|---|
| Size: | 100 μg/vial |
| Reactive Species: | Rat |
| Host: | Rabbit |
| Application: | IHC, WB |
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Product info
Product Name
Anti-Estrogen Inducible Protein pS2/TFF1 Antibody Picoband®
SKU/Catalog Number
PA1690
Size
100 μg/vial
Form
Lyophilized
Description
Boster Bio Anti-Estrogen Inducible Protein pS2/TFF1 Antibody catalog # PA1690. Tested in IHC, WB applications. This antibody reacts with Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Storage & Handling
Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-Estrogen Inducible Protein pS2/TFF1 Antibody Picoband® (Boster Biological Technology, Pleasanton CA, USA, Catalog # PA1690)
Host
Rabbit
Contents
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Clonality
Polyclonal
Isotype
Rabbit IgG
Immunogen
A synthetic peptide corresponding to a sequence in the middle region of mouse Estrogen Inducible Protein pS2, identical to the related rat sequence.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
No cross-reactivity with other proteins
Reactive Species
PA1690 is reactive to Tff1 in Rat
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Observed Molecular Weight
12 kDa
Calculated molecular weight
9670 MW
Background of TFF1/pS2
TFF1 (Trefoil factor 1), also known as pS2, is a protein that in humans is encoded by the TFF1 gene. Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. They are stable secretory proteins expressed in gastrointestinal mucosa. Their functions are not defined, but they may protect the mucosa from insults, stabilize the mucus layer, and affect healing of the epithelium. It is found that TFF1 in normal human urine inhibited the growth of calcium oxalate crystals. Urinary TFF1 showed an inhibitory potency similar to that of nephrocalcin, and inhibition was dose dependent and inhibited by TFF1 antisera, particularly by antisera directed to the TFF1 C terminus. Concentrations and relative amounts of TFF1 in the urine of patients with idiopathic calcium oxalate kidney stones were significantly less than those found in controls. This gene, which is expressed in the gastric mucosa, has also been studied because of its expression in human tumors. This gene and two other related trefoil family member genes are found in a cluster on chromosome 21.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
PA1690 is guaranteed for IHC, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Western blot, 0.1-0.5μg/ml, Rat
Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml, Rat, By Heat
Positive Control
WB: Rat Stomach Tissue
IHC: Rat Intestine Tissue
Validation Images & Assay Conditions
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Anti-Estrogen Inducible Protein pS2 antibody, PA1690, Western blotting
WB: Rat Stomach Tissue Lysate
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Anti-Estrogen Inducible Protein pS2 antibody, PA1690, IHC(P)
IHC(P): Rat Intestine Tissue
Protein Target Info & Infographic
Gene/Protein Information For Tff1 (Source: Uniprot.org, NCBI)
Gene Name
Tff1
Full Name
Trefoil factor 1
Weight
9670 MW
Alternative Names
Trefoil factor 1;Protein pS2;Tff1;Bcei, Ps2; TFF1 BCEI, D21S21, HP1.A, HPS2, pNR-2, pS2 trefoil factor 1 trefoil factor 1|breast cancer estrogen-inducible protein|breast cancer estrogen-inducible sequence|gastrointestinal trefoil protein pS2|polypeptide P1.A|protein pS2
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on Tff1, check out the Tff1 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for Tff1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Estrogen Inducible Protein pS2/TFF1 Antibody Picoband® (PA1690)
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Customer Reviews
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Customer Q&As
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1 Customer Q&As for Anti-Estrogen Inducible Protein pS2/TFF1 Antibody Picoband®
Question
Will the dimer form block the antigen epitope of this protein?
Verified Customer
Verified customer
Asked: 2018-04-04
Answer
We are not sure if the dimer form block the antigen epitope of this protein. We haven't experimentally verified this.
Boster Scientific Support
Answered: 2018-04-04
