Anti-ERV31/ERV3-1 Antibody

Product Name

Anti-ERV31/ERV3-1 Antibody

View all ERV3-1 Antibodies

SKU/Catalog Number

RP1091

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-ERV31/ERV3-1 Antibody catalog # RP1091. Tested in WB applications. This antibody reacts with Human.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-ERV31/ERV3-1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # RP1091)

Host

Rabbit

Contents

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

A synthetic peptide corresponding to a sequence at the C-terminus of human ERV31.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross-reactivity with other proteins

Reactive Species

RP1091 is reactive to ERV3-1 in Human

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Observed Molecular Weight

68 kDa

Calculated molecular weight

67942 MW

Background of ERV3-1

HERV-R_7q21.2 provirus ancestral Env polyprotein, also known as ERV3-1, is a protein that in humans is encoded by the ERV3 gene. By radiation hybrid analysis, the ERV3 gene is mapped to chromosome 7q11.2. The human genome includes many retroelements including the human endogenous retroviruses (HERVs). ERV3, one of the most studied HERVs, is thought to have integrated 30 to 40 million years ago and is present in higher primates with the exception of gorillas. Taken together, the observation of genome conservation, the detection of transcript expression, and the presence of conserved ORFs is circumstantial evidence for a functional role. A functional role is also suggested by the observation that downregulation of ERV3 is reported in choriocarcinoma.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

RP1091 is guaranteed for WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blot, 0.1-0.5μg/ml, Human

Positive Control

WB: HELA Whole Cell, 22RV1 Whole Cell, HEPG2 Whole Cell, SKOV Whole Cell, A431 Whole Cell, HT1080 Whole Cell

Validation Images & Assay Conditions

Gene/Protein Information For ERV3-1 (Source: Uniprot.org, NCBI)

Alternative Names

Endogenous retrovirus group 3 member 1 Env polyprotein;ERV-3 envelope protein;ERV3 envelope protein;ERV3-1 envelope protein;Envelope polyprotein;HERV-R envelope protein;ERV-R envelope protein;HERV-R_7q21.2 provirus ancestral Env polyprotein;Surface protein;SU;Transmembrane protein;TM;ERV3-1;ERV3; ERV3-1 ERV-R, ERV3, ERVR, HERV-R, HERVR, envR endogenous retrovirus group 3 member 1, envelope endogenous retrovirus group 3 member 1 Env polyprotein|ERV-R envelope protein|ERV3-1 envelope protein|HERV-R envelope protein|HERV-R_7q21.2 provirus ancestral Env polyprotein|endogenous retroviral sequence 3|endogenous retrovirus group 3, member 1

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

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