ERV3-1 Antibodies

AND ERV3-1 ELISA kits, ERV3-1 Proteins

Many biological assays use antibodies to detect ERV3-1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ERV3-1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ERV3-1 antibodies...

We validate the specificity of these antibodies to ERV3-1 by testing them on tissues known to express ERV3-1 positively and negatively. Browse below to find the ERV3-1 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ERV3-1 Infographic by Boster Bio

All ERV3-1 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-ERV31/ERV3-1 Antibody Picoband®

1 Q&As

Human

$370
Cat # RP1091
100 μg/vial

ERV31 (ERV3-1) (NM_001007253) Human Over-expression Lysate

Human

$960
Cat # LS002086
100 µg

ERV3-1 Overview

Facts about Endogenous retrovirus group 3 member 1 Env polyprotein.

ERV3-1 3D structure. Source: alphafold

Endogenous retrovirus group 3 member 1 Env polyprotein (ERV3-1)

Retroviral envelope proteins mediate receptor recognition and membrane fusion during early infection. Endogenous envelope proteins may have kept, lost or modified their original function during evolution.

This endogenous envelope protein has lost its fusogenic properties. It can inhibit cell growth through reduction expression of cyclin B1 and increased expression of p21 in vitro.

Gene Information

Human
Gene Name:	ERV3-1
Uniprot:	Q14264
Entrez:	2086

Family

Belongs to:

gamma type-C retroviral envelope protein family

Alternative Names

Endogenous Retroviral Sequence 3 (Includes Zinc Finger Protein H-Plk/HPF9); Endogenous Retroviral Sequence 3; Endogenous Retrovirus Group 3 Member 1 Env Polyprotein ; Endogenous Retrovirus Group 3 Member 1; Endogenous Retrovirus Group 3 Member 1, Envelope; Endogenous Retrovirus Group 3, Member 1; envelope polyprotein; ERV3 Envelope Protein; ERV-3 Envelope Protein; ERV3; ERV3-1 Envelope Protein; ERV-R Envelope Protein; ERV-R; HERVR; HERV-R; HERV-R_7q21.2 Provirus Ancestral Env Polyprotein

Molecular Weight

Mass (kDA):
67.942 kDA

Genomic Context


Human

Location:	7q11.21
Sequence:	7; NC_000007.14 (64990356..65006687, complement)

Tissue Specificity

Expressed at higher level in adrenal, sebaceous glands and placenta. Expressed at lower level in bone marrow, brain, breast, colon, heart, kidney, liver, lung, ovary, PBL, prostate, skin, spleen, testis, thymus, thyroid, trachea.

Subcellular Localizations

Virion.

PTMs

Cleavage on pair of basic residues

Disulfide bond

Glycoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ERV3-1

References

PMID: 3840930 by Cohen M., et al. The nucleotide sequence of the env gene from the human provirus ERV3 and isolation and characterization of an ERV3-specific cDNA.

PMID: 7645262 by Venables P.J.W., et al. Abundance of an endogenous retroviral envelope protein in placental trophoblasts suggests a biological function.