Anti-ERCC5/Xpg Antibody

Product Name

Anti-ERCC5/Xpg Antibody

View all XPG Antibodies

SKU/Catalog Number

A01770

Size

100 µl

Form

Liquid

Description

Boster Bio Anti-ERCC5/Xpg Antibody (Catalog # A01770). Tested in WB applications. This antibody reacts with Human.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-ERCC5/Xpg Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A01770)

Host

Rabbit

Contents

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from internal of human ERCC5.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross reactivity with other proteins.

Reactive Species

A01770 is reactive to ERCC5 in Human

Reconstitution

Calculated molecular weight

133108 MW

Background of XPG

Single-stranded structure-specific DNA endonuclease involved in DNA excision repair. Makes the 3'incision in DNA nucleotide excision repair (NER). Acts as a cofactor for a DNA glycosylase that removes oxidized pyrimidines from DNA. May also be involved in transcription-coupled repair of this kind of damage, in transcription by RNA polymerase II, and perhaps in other processes too.

Scherly D., Nature 363:182-185(1993).
Shiomi T., Mutat. Res. 314:167-175(1994).
Macinnes M.A., Mol. Cell. Biol. 13:6393-6402(1993).

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

A01770 is guaranteed for WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blotting: 1:500~1:3000

Validation Images & Assay Conditions

Gene/Protein Information For ERCC5 (Source: Uniprot.org, NCBI)

Alternative Names

DNA repair protein complementing XP-G cells;3.1.-.-;DNA excision repair protein ERCC-5;Xeroderma pigmentosum group G-complementing protein;ERCC5;ERCM2, XPG, XPGC; ERCC5 COFS3-201, ERCM2, UVDR, XPG, XPGC, ERCC5 ERCC excision repair 5, endonuclease DNA repair protein complementing XP-G cells|DNA excision repair protein ERCC-5|XPG-complementing protein|excision repair cross-complementation group 5|excision repair cross-complementing rodent repair deficiency, complementation group 5|xeroderma pigmentosum, complementation group G

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

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