Product Info Summary
SKU: | A10141 |
---|---|
Size: | 0.1 mg |
Reactive Species: | Human, Mouse |
Host: | Rabbit |
Application: | ELISA, IF, IHC-P, WB |
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Product info
Product Name
Anti-ELOVL7 Antibody
SKU/Catalog Number
A10141
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-ELOVL7 Antibody (Catalog # A10141). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse.
Storage & Handling
ELOVL7 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-ELOVL7 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A10141)
Host
Rabbit
Contents
ELOVL7 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
ELOVL7 antibody was raised against a 15 amino acid synthetic peptide near the amino terminus of human ELOVL7. The immunogen is located within amino acids 40 - 90 of ELOVL7.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
GDPD5 antibody is human, mouse and rat reactive. At least three isoforms of GDPD5 are known to exist.
Reactive Species
A10141 is reactive to ELOVL7 in Human, Mouse
Reconstitution
Observed Molecular Weight
68 kDa
Calculated molecular weight
33356 MW
Background of Elovl7
Lipogenesis is a key event in the energy storage system and is controlled by the transcription factor sterol regulatory element-binding protein (SREBP)-1. Elongation of very long chain fatty acids protein 7 (ELOVL7) is a member of fatty acyl-CoA elongase gene family that elongates saturated very-long-chain fatty acids (SVLFA, C20:0-) and has been suggested to be involved in prostate cancer growth through saturated long-chain fatty acid metabolism. The metabolic pathways of long-chain fatty acids play an important role in the maintenance of membrane lipid composition and the generation of cell signaling precursor molecules such as eicosanoids and sphingosine-1 phosphate. Overexpression of ELOVL7 results in lipid accumulation in differentiated adipocytes; its expression is regulated by the microRNA miR-219.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A10141 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
ELOVL7 antibody can be used for detection of ELOVL7 by Western blot at 1 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of ELOVL7 in human liver tissue lysate with ELOVL7 antibody at 1 μg/mL.
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Immunohistochemistry of ELOVL7 in human liver tissue with ELOVL7 antibody at 5 μg/mL.
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Immunofluorescence of ELOVL7 in human liver tissue with ELOVL7 antibody at 20 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For ELOVL7 (Source: Uniprot.org, NCBI)
Gene Name
ELOVL7
Full Name
Elongation of very long chain fatty acids protein 7
Weight
33356 MW
Superfamily
ELO family
Alternative Names
Elongation of very long chain fatty acids protein 7, 3-keto acyl-CoA synthase ELOVL7, ELOVL FA elongase 7
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on ELOVL7, check out the ELOVL7 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for ELOVL7: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-ELOVL7 Antibody (A10141)
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