Anti-Human CD147/Emmprin DyLight® 550 conjugated BSG Antibody

BSG antibody

Boster Bio Anti-Human CD147/Emmprin DyLight® 550 conjugated BSG Antibody catalog # A00248-Dyl550. Tested in Flow Cytometry applications. This antibody reacts with Human. Cited in 2 publication(s).

Product Info Summary

SKU: A00248-Dyl550
Size: 100 μg/vial
Reactive Species: Human
Host: Rabbit
Application: Flow Cytometry

Product Name

Anti-Human CD147/Emmprin DyLight® 550 conjugated BSG Antibody

View all BSG Antibodies

SKU/Catalog Number

A00248-Dyl550

Size

100 μg/vial

Form

Liquid

Description

Boster Bio Anti-Human CD147/Emmprin DyLight® 550 conjugated BSG Antibody catalog # A00248-Dyl550. Tested in Flow Cytometry applications. This antibody reacts with Human.

Storage & Handling

At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Cite This Product

Anti-Human CD147/Emmprin DyLight® 550 conjugated BSG Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A00248-Dyl550)

Host

Rabbit

Contents

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

E.coli-derived human CD147/Emmprin recombinant protein (Position: E138-A323). Human CD147/Emmprin shares 51.1% and 51.9% amino acid (aa) sequence identity with mouse and rat CD147/Emmprin, respectively.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross-reactivity with other proteins.

Reactive Species

A00248-Dyl550 is reactive to BSG in Human

Reconstitution

Observed Molecular Weight

39 kDa

Calculated molecular weight

42.2kDa

Background of BSG

Emmprin, extracellular matrix metalloproteinase inducer, also known as Emmprin (BSG) or cluster of differentiation 147 (CD147) is a protein that in humans is encoded by the Emmprin gene. The human BSG gene is mapped to 19p13.3. This protein is a determinant for the Ok blood group system. BSG has been shown to be an essential receptor on red blood cells for the malaria parasite. It is a member of the immunoglobulin superfamily, with a structure related to the putative primordial form of the family. As members of the immunoglobulin superfamily, it plays fundamental roles in intercellular recognition involved in various immunologic phenomena, differentiation, and development. BSG is thought also to play a role in intercellular recognition. It also regulates several distinct functions, such as spermatogenesis, expression of the monocarboxylate transporter and the responsiveness of lymphocytes. BSG is a type I integral membrane receptor that has many ligands, including the cyclophilin (CyP) proteins Cyp-A and CyP-B and certain integrins. It is expressed by many cell types, including epithelial cells, endothelial cells and leukocytes.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

A00248-Dyl550 is guaranteed for Flow Cytometry Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Flow Cytometry (Fixed), 1-3μg/1x106 cells

Validation Images & Assay Conditions

Gene/Protein Information For BSG (Source: Uniprot.org, NCBI)

Gene Name

BSG

Full Name

Basigin

Weight

42.2kDa

Alternative Names

Basigin; 5F7; Collagenase stimulatory factor; Extracellular matrix metalloproteinase inducer; EMMPRIN; Leukocyte activation antigen M6; OK blood group antigen; Tumor cell-derived collagenase stimulatory factor; TCSF; CD147; BSG; UNQ6505/PRO21383 BSG 5F7, CD147, EMMPRIN, EMPRIN, HAb18G, OK, SLC7A11, TCSF basigin (Ok blood group) basigin|OK blood group |collagenase stimulatory factor|extracellular matrix metalloproteinase inducer|hepatoma-associated |leukocyte activation M6|tumor cell-derived collagenase stimulatory factor

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on BSG, check out the BSG Infographic

BSG infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for BSG: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

Hello CJ!

A00248-Dyl550 has been cited in 2 publications:

*The publications in this section are manually curated by our staff scientists. They may differ from Bioz's machine gathered results. Both are accurate. If you find a publication citing this product but is missing from this list, please let us know we will issue you a thank-you coupon.

Lu Q, Lv G, Kim A, Ha Jm, Kim S. Oncol Lett. 2013 Jan;5(1):201-207. Epub 2012 Oct 19. Expression And Clinical Significance Of Extracellular Matrix Metalloproteinase Inducer, Emmprin/Cd147, In Human Osteosarcoma.

Ying Hz, Liu Yh, Yu B, Wang Zy, Zang Jn, Yu Ch. Food Chem Toxicol. 2013 Feb;52:53-60. Doi: 10.1016/J.Fct.2012.10.030. Epub 2012 Nov 2. Dietary Quercetin Ameliorates Nonalcoholic Steatohepatitis Induced By A High-Fat Diet In Gerbils.

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3 Customer Q&As for Anti-Human CD147/Emmprin DyLight® 550 conjugated BSG Antibody

Question

Here is the WB image, lot number and protocol we used for apex of heart using anti-Human CD147/Emmprin DyLight® 550 conjugated antibody A00248-Dyl550. Please let me know if you require anything else.

Verified Customer

Verified customer

Asked: 2019-10-11

Answer

Thank you very much for the data. Our lab team are working to resolve this as quickly as possible, and we appreciate your patience and understanding! You have provided everything we needed. Please let me know if there is anything you need in the meantime.

Boster Scientific Support

Answered: 2019-10-11

Question

Is a blocking peptide available for product anti-Human CD147/Emmprin DyLight® 550 conjugated antibody (A00248-Dyl550)?

J. Jones

Verified customer

Asked: 2018-07-20

Answer

We do provide the blocking peptide for product anti-Human CD147/Emmprin DyLight® 550 conjugated antibody (A00248-Dyl550). If you would like to place an order for it please contact [email protected] and make a special request.

Boster Scientific Support

Answered: 2018-07-20

Question

We appreciate helping with my inquiry over the phone. Here are the WB image, lot number and protocol we used for apex of heart using anti-Human CD147/Emmprin DyLight® 550 conjugated antibody A00248-Dyl550. Let me know if you need anything else.

Verified Customer

Verified customer

Asked: 2017-09-26

Answer

I appreciate the data. You have provided everything we needed. Our lab team are working to resolve your inquiry as quickly as possible, and we appreciate your patience and understanding! Please let me know if there is anything you need in the meantime.

Boster Scientific Support

Answered: 2017-09-26

Order DetailsPrice
A00248-Dyl550

100μg

$515
A00248-Dyl550-carrier-free

Carrier Free

$515

Free Secondary Antibody

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A00248-Dyl550
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*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$515.00

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