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Product Info Summary
| SKU: | A06004-1 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, IF, IHC-P, WB |
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Product info
Product Name
Anti-ELOVL6 Antibody
SKU/Catalog Number
A06004-1
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-ELOVL6 Antibody (Catalog # A06004-1). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
ELOVL6 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-ELOVL6 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A06004-1)
Host
Rabbit
Contents
ELOVL6 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
ELOVL6 antibody was raised against a 15 amino acid synthetic peptide near the amino terminus of the human ELOVL6. The immunogen is located within the first 50 amino acids of ELOVL6.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
PMEPA1 antibody is human, mouse and rat reactive. At least four isoforms are known to exist; this antibody will detect all of the isoforms.
Reactive Species
A06004-1 is reactive to ELOVL6 in Human, Mouse, Rat
Reconstitution
Observed Molecular Weight
68 kDa
Calculated molecular weight
31376 MW
Background of ELOVL6
Lipogenesis is a key event in the energy storage system and is controlled by the transcription factor sterol regulatory element-binding protein (SREBP)-1. Elongation of very long chain fatty acids protein 6 (ELOVL6) is a member of fatty acyl-CoA elongase gene family that converts palmitic to stearic acid and it has been shown to be a target of SREBP-1, playing an important role in de novo synthesis of long-chain saturated and monosaturated fatty acids in conjunction with fatty acid synthase and stearoyl-CoA desaturase ELOVL6 was predicted to be important for tissue fatty acid composition. Recent studies suggest that inhibition of this elongase could be a new therapeutic approach for ameliorating insulin resistance, diabetes and cardiovascular risks, even in the presence of a continuing state of obesity.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A06004-1 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
ELOVL6 antibody can be used for detection of ELOVL6 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of ELOVL6 in Human brain tissue lysate with ELOVL6 antibody at (A) 1 and (B) 2 μg/mL.
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Immunohistochemistry of ELOVL6 in human brain tissue with ELOVL6 antibody at 5 μg/mL.
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Immunofluorescence of ELOVL6 in Human Brain tissue with ELOVL6 antibody at 20 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For ELOVL6 (Source: Uniprot.org, NCBI)
Gene Name
ELOVL6
Full Name
Elongation of very long chain fatty acids protein 6
Weight
31376 MW
Superfamily
ELO family
Alternative Names
FAE, LCE, FACE, Elongation of very long chain fatty acids protein 6, 3-keto acyl-CoA synthase ELOVL6, ELOVL FA elongase 6 ELOVL6 FACE, FAE, LCE ELOVL fatty acid elongase 6 elongation of very long chain fatty acids protein 6|3-keto acyl-CoA synthase ELOVL6|ELOVL FA elongase 6|ELOVL family member 6, elongation of long chain fatty acids (FEN1/Elo2, SUR4/Elo3-like, yeast)|fatty acid elongase 2|fatty acyl-CoA elongase|hELO2|long-chain fatty-acyl elongase|very long chain 3-ketoacyl-CoA synthase 6|very long chain 3-oxoacyl-CoA synthase 6
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on ELOVL6, check out the ELOVL6 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for ELOVL6: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-ELOVL6 Antibody (A06004-1)
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