Product Info Summary
SKU: | A00069-1 |
---|---|
Size: | 100ul |
Reactive Species: | Human, Mouse, Rat |
Host: | Rabbit |
Application: | IHC, WB |
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Product info
Product Name
Anti-Dystrophin DMD Antibody
View all Dystrophin Antibodies
SKU/Catalog Number
A00069-1
Size
100ul
Form
Liquid
Description
Boster Bio Anti-Dystrophin DMD Antibody catalog # A00069-1. Tested in WB,IHC applications. This antibody reacts with Human,Mouse,Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-Dystrophin DMD Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A00069-1)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from human CD40 around the phosphorylation site of T254.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
No cross reactivity with other proteins.
Reactive Species
A00069-1 is reactive to DMD in Human, Mouse, Rat
Applications
A00069-1 is guaranteed for IHC, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
426750 MW
Background of Dystrophin
This antibody is suitable for Cancer, Immunology and Nuclear Signaling research. ATP-Binding Cassette Sub-Family B Member 1 (ABCB1, also named P-glycoprotein) is a plasma membrane-associated multidrug transporter that utilizes the energy of ATP hydrolysis to pump toxic xenobiotics out of cells. Unique features of ABCB1 are its very broad substrate specificity and its basal ATPase activity in the absence of transport substrates. Human ABCB1 plays an important role in absorption, distribution, metabolism, excretion and toxicity of pharmacologically relevant drugs. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anti-cancer drugs. This protein also functions as a transporter across the blood-brain barrier.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:1,000
IHC: 1:50-1:200
Validation Images & Assay Conditions
![a00069 1 anti dystrophin dmd antibody ihc testing 1 a00069 1 anti dystrophin dmd antibody ihc testing 1](https://www.bosterbio.com/media/catalog/product/a/0/a00069-1-anti-dystrophin-dmd-antibody-ihc-testing-1.jpg)
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Immunohistochemical analysis of paraffin-embedded mouse skeletal muscle tissue using anti-Dystrophin antibody. Counter stained with hematoxylin.
![a00069 1 anti dystrophin dmd antibody ihc testing 2 a00069 1 anti dystrophin dmd antibody ihc testing 2](https://www.bosterbio.com/media/catalog/product/a/0/a00069-1-anti-dystrophin-dmd-antibody-ihc-testing-2.jpg)
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Immunohistochemical analysis of paraffin-embedded mouse brain tissue using anti-Dystrophin antibody. Counter stained with hematoxylin.
Protein Target Info & Infographic
Gene/Protein Information For DMD (Source: Uniprot.org, NCBI)
Gene Name
DMD
Full Name
Dystrophin
Weight
426750 MW
Alternative Names
BMDDXS272; CMD3B; DXS142; DXS164; DXS164, DXS206, DXS230, DXS239, DXS268, DXS269, DXS270, DXS272; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; dystrophin (muscular dystrophy, Duchenne and Becker types), includes DXS142; dystrophin DMD BMD, CMD3B, DXS142, DXS164, DXS206, DXS230, DXS239, DXS268, DXS269, DXS270, DXS272, MRX85 dystrophin dystrophin|truncated dystrophin
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on DMD, check out the DMD Infographic
![DMD infographic](/media/images/gene-infographic-example.jpg)
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for DMD: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Dystrophin DMD Antibody (A00069-1)
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No publications found for A00069-1
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