Anti-CYP8B1 Antibody

Product Name

Anti-CYP8B1 Antibody

View all CYP8B1 Antibodies

SKU/Catalog Number

A05518-1

Size

100μl

Form

Liquid

Description

Boster Bio Anti-CYP8B1 Antibody catalog # A05518-1. Tested in ELISA, IHC-P, WB applications. This antibody reacts with Human, Mouse.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-CYP8B1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A05518-1)

Host

Rabbit

Contents

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from the Internal region of human CYP8B1. at AA rangle: 340-420

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross reactivity with other proteins.

Reactive Species

A05518-1 is reactive to CYP8B1 in Human, Mouse

Applications

A05518-1 is guaranteed for ELISA, IHC-P, WB Boster Guarantee

Observed Molecular Weight

39 kDa

Calculated molecular weight

58068 MW

Background of CYP8B1

Heme oxygenase 2 (HMOX2), also known as HO-2, is an enzyme that in humans is encoded by the HMOX2 gene. It is mapped to 16p13.3. HMOX2 belongs to the heme oxygenase family. Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed. Heme oxygenase 2 could be implicated in the production of carbon monoxide in brain where it could act as a neurotransmitter.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:40000

Validation Images & Assay Conditions

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Western Blot (WB) analysis of specific cells using CYP8B1 Polyclonal antibody.

Gene/Protein Information For CYP8B1 (Source: Uniprot.org, NCBI)

Alternative Names

7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase CYP8B1 CP8B, CYP12 cytochrome P450 family 8 subfamily B member 1 7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase|7 alpha-hydroxy-4-cholesten-3-one 12-alpha-hydroxylase|CYPVIIIB1|cytochrome P450 8B1|cytochrome P450, family 8, subfamily B, polypeptide 1|cytochrome P450, subfamily VIIIB (sterol 12-alpha-hydroxylase), polypeptide 1|sterol 12-alpha-hydroxylase

For more info on CYP8B1, check out the CYP8B1 Infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for CYP8B1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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