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Product Info Summary
| SKU: | A01331 |
|---|---|
| Size: | 100 µl |
| Reactive Species: | Human |
| Host: | Rabbit |
| Application: | IHC |
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Product info
Product Name
Anti-CTRO CIT Antibody
View all Citron Kinase Antibodies
SKU/Catalog Number
A01331
Size
100 µl
Form
Liquid
Description
Boster Bio Anti-CTRO CIT Antibody (Catalog # A01331). Tested in IHC applications. This antibody reacts with Human.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-CTRO CIT Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A01331)
Host
Rabbit
Contents
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from internal of human CTRO.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
No cross reactivity with other proteins.
Reactive Species
A01331 is reactive to CIT in Human
Reconstitution
Calculated molecular weight
231431 MW
Background of Citron Kinase
Plays a role in cytokinesis. Required for KIF14 localization to the central spindle and midbody. Putative RHO/RAC effector that binds to the GTP-bound forms of RHO and RAC1. It probably binds p21 with a tighter specificity in vivo. Dual specificity protein kinase activity catalyzing autophosphorylation and phosphorylation of exogenous substrates on both serine/threonine and tyrosine residues. Plays an important role in the regulation of cytokinesis and the development of the central nervous system. Phosphorylates MYL9/MLC2.
Nagase T., DNA Res. 6:63-70(1999).
Scherer S.E., Nature 440:346-351(2006).
Gruneberg U., J. Cell Biol. 172:363-372(2006).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A01331 is guaranteed for IHC Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Immunohistochemistry: 1:50~1:100
Validation Images & Assay Conditions
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Immunohistochemistry analysis of paraffin-embedded human brain tissue using CTRO antibody A01331.
Protein Target Info & Infographic
Gene/Protein Information For CIT (Source: Uniprot.org, NCBI)
Gene Name
CIT
Full Name
Citron Rho-interacting kinase
Weight
231431 MW
Superfamily
protein kinase superfamily
Alternative Names
Citron Rho-interacting kinase;CRIK;2.7.11.1;Serine/threonine-protein kinase 21;CIT;CRIK, KIAA0949, STK21; CIT CITK, CRIK, MCPH17, STK21 citron rho-interacting serine/threonine kinase citron Rho-interacting kinase|citron (rho-interacting, serine/threonine kinase 21)|serine/threonine kinase 21|serine/threonine-protein kinase 21
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on CIT, check out the CIT Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for CIT: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-CTRO CIT Antibody (A01331)
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No publications found for A01331
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Customer Reviews
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Customer Q&As
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3 Customer Q&As for Anti-CTRO CIT Antibody
Question
I was wanting to use your anti-CTRO antibody for IHC for human brain on frozen tissues, but I want to know if it has been tested for this particular application. Has this antibody been tested and is this antibody a good choice for human brain identification?
Verified Customer
Verified customer
Asked: 2019-05-21
Answer
You can see on the product datasheet, A01331 anti-CTRO antibody has been tested for IHC on human tissues. We have an innovator award program that if you test this antibody and show it works in human brain in IHC-frozen, you can get your next antibody for free.
Boster Scientific Support
Answered: 2019-05-21
Question
I have a question about product A01331, anti-CTRO antibody. I was wondering if it would be possible to conjugate this antibody with biotin. I would need it to be without BSA or sodium azide. I am planning on using a buffer exchange of sodium azide with PBS only. Would there be problems for me to conjugate the antibody and store it in -20 degrees in small aliquots?
Verified Customer
Verified customer
Asked: 2018-01-19
Answer
It is not recommended storing this antibody with PBS buffer only in -20 degrees. If you want to store it in -20 degrees it is best to add some cryoprotectant like glycerol. If you want carrier free A01331 anti-CTRO antibody, we can provide it to you in a special formula with trehalose and/or glycerol. These molecules will not interfere with conjugation chemistry and provide a good level of protection for the antibody from degradation. Please be sure to specify this in your purchase order.
Boster Scientific Support
Answered: 2018-01-19
Question
We are currently using anti-CTRO antibody A01331 for human tissue, and we are satisfied with the IHC results. The species of reactivity given in the datasheet says human. Is it likely that the antibody can work on horse tissues as well?
C. Bhatt
Verified customer
Asked: 2017-11-29
Answer
The anti-CTRO antibody (A01331) has not been tested for cross reactivity specifically with horse tissues, but there is a good chance of cross reactivity. We have an innovator award program that if you test this antibody and show it works in horse you can get your next antibody for free. Please contact me if I can help you with anything.
Boster Scientific Support
Answered: 2017-11-29
