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- Table of Contents
Facts about Citron Rho-interacting kinase.
Putative RHO/RAC effector that binds to the GTP-bound forms of RHO and RAC1. It probably binds p21 with a tighter specificity in vivo.
Human | |
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Gene Name: | CIT |
Uniprot: | O14578 |
Entrez: | 11113 |
Belongs to: |
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protein kinase superfamily |
CITK; citron (rho-interacting, serine/threonine kinase 21); Citron Rho-Interacting Kinase; Citron Rho-Interacting Serine/Threonine Kinase; CRIK; KIAA0949; MCPH17; Rho-interacting Serine/Threonine kinase 21; serine/threonine kinase 21; Serine/threonine-protein kinase 21; STK21
Mass (kDA):
231.431 kDA
Human | |
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Location: | 12q24.23 |
Sequence: | 12; NC_000012.12 (119685791..119877320, complement) |
Cytoplasm.
PMID: 15983625 by Lyons-Warren A., et al. Evidence of association between bipolar disorder and Citron on chromosome 12q24.
PMID: 16431929 by Gruneberg U., et al. KIF14 and citron kinase act together to promote efficient cytokinesis.